Genomics of Pattern Recognition Receptors: Applications in Oncology and Cardiovascular Diseases

Kutikhin, Anton G.; Yuzhalin, Arseniy E.

This book offers comprehensive information on the polymorphisms of genes encoding pattern recognition receptors (PRRs). Following a short description of the general role of PRRs in the immune system, the structure and function of Toll-like and NOD-like receptors are examined in detail. The main focus is on the role of inherited variation in PRRs and their correlation to cancer and cardiovascular diseases. A review of all epidemiological investigations is included, and a concept of genomic risk markers for the prevention of various diseases is also discussed.

Details

Published by: Springer

Publication Date: 2013-09-10

Format: Hardcover

ISBN-13: 9783034806879

DOI: 10.1007/978-3-0348-0688-6

Dimensions: 235cm x155cm

Pages: 185