This thoroughly revised fourth edition provides a comprehensive grounding on hereditary heart diseases with special emphasis on the genetic aspects of these conditions. It continues to provide the expertise that all cardiologists, clinical and molecular geneticists, and related medical professionals require to provide optimal care for patients with cardiac disease of genetic origin and for their relatives. Topics covered include the different cardiomyopathies, the primary arrhythmia syndromes and the hereditary thoracic aortic disorders. In addition other topics such as cardiac involvement in hereditary neuromuscular diseases, the clinical policy for sudden cardiac death and the possibilities of pre-implantation genetic diagnosis are included to extend the discussion.

Clinical Cardiogenetics compiles current knowledge on the topic in an easy to understand reference. It provides a practical clinical primer and represents essential reader for cardiologists, clinical geneticists, trainees and other physicians involved in the management of these patients.

Arjan C. Houweling is a clinical geneticist and Associate Professor in the Department of Human Genetics at Amsterdam UMC, Free University, Amsterdam, The Netherlands. Since 2007, he has specialized in hereditary cardiovascular diseases, combining clinical care with genetic and translational research. His research focuses on identifying novel disease genes, establishing genotype–phenotype correlations, and translating genetic observations into improving diagnostics and patient care for individuals and families with inherited cardiovascular disorders.

Karin van Spaendonck-Zwarts is a clinical geneticist and head of the Clinical Genetics Outpatient Clinic at Leiden University Medical Center. Within her department, a team of more than forty professionals works together to provide patients and their families with the best possible genetic care for (suspected) genetic disorders. Close collaboration with other medical specialists and laboratory specialists is essential. After studying Medicine and Medical Biology, she completed her training as a clinical geneticist in 2008. Since then, she has gained broad experience in various sub-areas of genetics and developed specific expertise in cardiovascular genetics. Her scientific research focuses on further unraveling the genetic causes of heart muscle diseases and mapping the risks for family members, with the ultimate goal of preventing and more targeted treatment of these conditions.