This book provides a comprehensive overview of multifunctional 3D-engineered polysaccharide materials for advanced medical, healthcare, diagnostic, and biosensing applications, showcasing their transformative potential as next-generation platforms for drug delivery, regenerative medicine, disease diagnosis, and intelligent sensing technologies. Owing to their biocompatibility, biodegradability, tunable structures, and versatile functionality, these materials have emerged as promising candidates for a broad range of medical, healthcare, and sensing applications. The book highlights a wide range of engineered material formats, including hydrogels, aerogels, cryogels, xerogels, scaffolds, sponges, foams, bioinks, and 3D/4D-printed systems, emphasizing their design principles, functional properties, and practical applications.

The contents are organized into three thematic parts: drug delivery applications; regenerative medicine and tissue engineering; and sensing and biosensing technologies. Contributions from leading experts provide both fundamental insights and recent advances in the field, including smart responsive materials, self-healing systems, advanced biofabrication, 3D bioprinting, wearable sensors, and diagnostic platforms.

Responding to the growing interest in 3D-engineered polysaccharide materials, this book provides a unified reference integrating recent advances in medical, healthcare, and sensing applications. It serves as a valuable and comprehensive resource for researchers, graduate students, educators, and industry professionals involved in developing sustainable materials for next-generation healthcare, biomedical, and sensing technologies.

Dr. Mahmoud H. Abu Elella is a Lecturer in Polymer Chemistry at the Chemistry Department, Faculty of Science, Cairo University, Egypt. He received both his M.Sc. and Ph.D. in Polymer Chemistry from the same institution in 2016 and 2019, respectively. Recently, he joined the School of Chemistry and Pharmacy at the University of Reading, UK, as a Postdoctoral Researcher. With over 12 years of research experience in Polymer Science, his work has focused on the synthesis and development of polymer formulations, including grafted copolymers, hydrogels, scaffold materials, polymer nanocomposites, nanoparticles, nanostructured lipid nanoparticles, polymer-coated liposomes, nanoemulsions, polymer-coated silica nanoparticles, and spray-dried microparticle powders for biomedical applications. 
He has also developed mucoadhesive inhalable polymeric powders using two-fluid and three-fluid nozzle spray drying techniques for pulmonary and nasal drug delivery. He has a strong record of interdisciplinary collaboration, project leadership, scientific publication (50+ manuscripts and 25 book chapters, h-index 32), and grant-supported research. He has been recognized as one of the World’s Top 2% Scientists (2023-2025). He is experienced in regulatory compliance, analytical characterization, and academic-industry knowledge transfer. He has actively presented his research at several international conferences and seminars, serves as a peer reviewer for high-impact journals, and acts as a lead editor for several edited and authored books with reputable publishers, such as Elsevier, Wiley, Springer, and ACS.

Prof. Dr. Riham R. Mohamed is a full professor of Polymer Chemistry at the Faculty of Science, Cairo University, Egypt, with over 28 years of experience in polymer research. Post Doc visitor in both Heinrich-Heine University Düsseldorf, Germany, and UMass Amherst, USA. Her work focuses on the fabrication of hydrogels and nanocomposites for wastewater treatment, drug delivery systems, and the modification of natural polymers for wound healing. 
She has been teaching both graduate and undergraduate students in science, dental, and pharmacy programs, specifically in “Organic Chemistry” and “Polymer Technology,” since 1999 at Cairo University, MSA University, and Zewail University. Prof Ali has also conducted extensive research, having completed her master’s and Ph.D. theses in polymer science. She has supervised more than 60 master’s and Ph.D. theses in the field of Polymer Technology, published more than 75 scientific research articles in international high-ranked journals, and 17 chapters in international books. Prof Ali has been awarded 3 prizes in Chemistry: the Cairo University award, State Encouragement Award, and Excellence Award (2012, 2014, 2018). She has been recognized as one of the World’s Top 2% Scientists (2023-2025). Prof. Ali leads a strong Polymer Lab with a highly qualified team at the Faculty of Science, Cairo University.

Dr. Nedal Y. Abu-Thabit is an associate professor in the chemical engineering department at Jubail Industrial College, Saudi Arabia. From 2013 to 2018, he was the program director for the Polymer Engineering Technology major. Dr. Nedal has published over 60 research articles and reviews in high-ranked and refereed ISI journals. His research interests are in the interdisciplinary areas of material science, chemistry, nanotechnology, and macromolecular chemistry. Dr. Nedal focuses on applications related to sustainable material developments, green chemistry, water/oil separation, optical chemical sensors, electroactive polymers, isolation and utilization of biopolymers, coatings, and educational chemistry and polymer chemistry. Dr. Nedal has published 4 books and 16 book chapters related to smart materials for diverse advanced technological and industrial applications.