This three-volume set constitutes the revised selected papers from the 5th International Conference on Advanced Research in Technologies, Information, Innovation and Sustainability 2025, ARTIIS 2025, held in Cartagena de Indias, Colombia, during October 21–23, 2025.

The 91 full papers and 10 short papers included in these proceedings were carefully reviewed and selected from 266 submissions. These papers were categorized under the following topical sections:

Part I: Computing Solutions.
Part II: Data Intelligence.
Part III: Sustainability; Ethics, Security, and Privacy.