Therapeutic Intranasal Delivery for Stroke and Neurological Disorders

Chen, Jun; Wang, Jian; Wei, Ling; Zhang, John H.

The blood-brain-barrier serves to encapsulate and protect the central nervous system, but it also presents a major barricade to therapeutic drug delivery. Poor penetration is the most common hurdle to translating a promising experimental therapy that uses invasive delivery methods to a clinically useful application. In the last 10 years, intranasal delivery of various therapeutic compounds including small chemicals, large proteins, and even stem cells has proven to be very effective in bypassing the blood-brain-barrier and has led to some important advances in translational research for stroke and other neurological diseases. The proposed book will bring together reports from various labs around the world who have had successes in pre-clinical studies of intranasal therapies for various diseases including adult and perinatal stroke, Alzheimer's, Parkinson's, and others.​

Details

Published by: Springer

Publication Date: 2019-06-17

Format: Hardcover

ISBN-13: 9783030167134

DOI: 10.1007/978-3-030-16715-8

Dimensions: 235.0cm x155.0cm

Pages: 153.0