The collection of systems represented in this volume is an effort to reflect the diversity and utility of models that are used in biomedicine. That utility is based on the consideration that observations made in particular organisms will provide insight into the workings of other, more complex systems. This is a comprehensive and extensive collection of these important medical parallels. While the entire book is not devoted to the remarkable success of the genomic programs, this work is well represented and indexed. This volume will be an invaluable resource for pharmaceutical and academic researchers across a wide range of biological fields.