Written by leading research scientists, this book integrates current knowledge of toxicology and human health through coverage of environmental toxicants, genetic / epigenetic mechanisms, and carcinogenicity.

• Provides information on lifestyle choices that can reduce cancer risk
• Offers a systematic approach to identify mutagenic, developmental and reproductive toxicants
• Helps readers develop new animal models and tests to assess toxic impacts of mutation and cancer on human health
• Explains specific cellular and molecular targets of known toxicants operating through genetic and epigenetic mechanisms

MICHAEL D. WATERS, PhD, is an independent consultant with over 40 years of toxicology and toxicogenomics research experience at the EPA, at NIH/NIEHS and in the private sector. He has held adjunct professorships in toxicology and pharmacology at both the University of North Carolina and Duke University.

CLAUDE L. HUGHES, MD, PhD, is an Executive Director in the Therapeutic Science and Strategy Unit at QuintilesIMS. He is also an Adjunct Professor at North Carolina State University, and Wake Forest University as well as a Consulting Professor at Duke University Medical Center.