Multivolume encyclopedia on the evolution and applications of organopalladium chemistry

Palladium in Organic Synthesis is a five-volume encyclopedia that covers how palladium, a special metal, is used to help scientists build and change organic molecules. It reviews the history and development of palladium chemistry, showing how it can turn simple chemicals into more complex ones through different reactions.

The chapters explain how palladium helps make rings, chains, and other structures found in medicines, plastics, and advanced materials. The book describes important reactions like cross-coupling, oxidation, and carbonylation, which are essential for making new drugs and materials. Each chapter focuses on a different type of reaction or chemical group, giving researchers practical knowledge and examples.

Palladium in Organic Synthesis discusses:

• Palladium π-Olefin Chemistry, palladium π-Alkyne chemistry, π-AllylPalladium chemistry, and π-Allenic and -Propargylic palladium chemistry
• Oxidative addition, alkane cross-coupling, alkene insertion (Mizoroki-Heck reaction), and reactions involving dienes, trienes, and polyenes
• Reactions with alkynes and arynes, coupling of organic halides, sulfonates, sulfonyl halides, and related compounds with arenes and heteroarenes, and coupling of two organic halides, triflates, or other groups
• Isonitrile insertion, carbonyl, imine, nitrile, CO2, and SO2 additions, and reactions with carboxylic and sulfinic acids
• Cross-coupling with organometallics, covering organoboranes (Suzuki-Miyaura reaction), organosilanes (Hiyama reaction), organostannanes (Stille reaction), and organozinc reagents (Negishi reaction)

Bringing together the latest methods and discoveries, Palladium in Organic Synthesis is an essential up-to-date reference for students and scientists to design new experiments and solve tough problems in organic chemistry.

Richard C. Larock, PhD, is University Professor and Distinguished Professor of Chemistry Emeritus at Iowa State University. He is a pioneer in the use of palladium catalysts in organic synthesis, particularly in the synthesis of carbocycles and heterocycles.

William H. Gong, PhD, is a Senior Research Scientist at BP and a Senior Principal Scientist at Origin Materials. He has expertise in organic chemical reaction mechanisms and the development and applications of homogeneous and heterogeneous catalysis for oxidation.