This book is the first in a groundbreaking series exploring the innovative realm of High Intensity Focused Ultrasound (HIFU) surgical treatments. It serves as an essential reference for students, scientists, engineers, and clinicians eager to understand and apply minimally invasive and non-invasive focused ultrasound therapy. This volume delves into the fundamentals of HIFU therapy, covering critical topics such as transducers, ultrasound tissue properties, and induced bioeffects.

Key concepts include the principles of HIFU thermal ablation, the physical mechanisms behind it, and the critical issues for successful application. The book provides a comprehensive guide to ultrasound-guided HIFU treatment for benign gynecological diseases, detailing pretreatment preparation, step-by-step procedures, precautions, results, and potential complications. Readers will gain insights into the treatment of conditions such as uterine fibroids, adenomyosis, and abnormal placental attachment, among others.

Gynecological surgeons, HIFU researchers, and surgeons interested in non-invasive surgery development will find this book invaluable. It offers a detailed exploration of HIFU applications in gynecology, many of which are seldom practiced or reported in the literature, making it a must-read for those at the forefront of medical innovation.

Felix Wu Shun Wong

Felix Wong currently serves as an Adjunct Professor at the NICM Health Research Institute, Western Sydney University. He previously held the position of Professor and Medical Director at Liverpool Hospital, University of New South Wales, Sydney, Australia. In 2009, he was awarded the Endos Award in Medical Science and Technology by China for his outstanding achievement in endoscopic surgery. In 2017, the Chinese Obstetricians and Gynecologists Association (COGA) honored him with the Lin Qiaozhi Cup for his significant contributions to obstetrics and gynecology in China. The same year, he received the Lifetime Achievement Award from the Asia-Pacific Association for Gynecologic Endoscopy and Minimally Invasive Therapy (APAGE). In 2018, the European Society for Gynaecological Endoscopy (ESGE) presented him with the Outstanding Contribution Award. Professor Wong has edited 14 medical books, including 4 on HIFU therapy. He published over 250 papers in local and international journals. Despite his notable contributions to endoscopic surgery, he continues to advance HIFU education and services in China and across the Asia-Pacific region.

Wenzhi CHEN

Wenzhi CHEN obtained his degree from Chongqing Medical University in 1984, followed by a Master's in Medicine in 1992. From 1984 to 2021, he held positions as Deputy Chief Physician in Orthopedics and Chief Physician at the Oncology Center of the Second Affiliated Hospital of Chongqing Medical University. In addition, he served as a researcher at the University's Ultrasound Research Institute and as Director of its Clinical Research Laboratory. Since 2021, he has been leading clinical research at the National Key Laboratory of Ultrasound in Medicine and Engineering.

Dr. Chen developed the Focused Ultrasound Tumor Therapeutic System and has been actively involved in its clinical application since 1997. He significantly contributed to device development and clinical protocol design and holds 20 patents, including 14 international ones. His innovative work has earned him various national and local awards.

As an expert trainer, Dr. Chen has worked extensively on HIFU treatment protocols, advancing its clinical applications both in China and internationally. He established a proficient HIFU physician team and is an esteemed member of numerous academic organizations. His research primarily focuses on surgery and oncology, and he has co-authored eight books, led three national projects, and published 242 research papers.

Lian ZHANG

Lian Zhang graduated from Chongqing Medical University in 1987. In 1998, he pursued further studies at the University of California, San Diego (UCSD), before returning to China in 2004 to join the Oncology Center of the Second Hospital affiliated with Chongqing Medical University. As a chief researcher, he played a significant role in developing the High-Intensity Focused Ultrasound (HIFU) system and has led or participated in numerous scientific research projects, earning multiple city-level and national awards.

Currently, Dr. Zhang holds the position of Medical Director at the Chongqing HIFU Hospital. He is responsible for training HIFU surgeons worldwide and serves as Secretary General of the International Society of Minimally Invasive and Virtual Surgery. He is also a member of the Minimally Invasive and Non-invasive Medical Committee of the Chinese Medical Doctor Association.

Dr. Zhang's research interests encompass anatomy, molecular biology, oncology, and related fields. He has authored over 80 papers in peer-reviewed journals and serves as a section editor for the International Journal of Hyperthermia.