{"product_id":"9789811374524","title":"Actin Polymerization in Apicomplexan: A Structural, Functional and Evolutionary Analysis","description":"\u003ch1\u003eActin Polymerization in Apicomplexan: A Structural, Functional and Evolutionary Analysis\u003c\/h1\u003e \u003ch2\u003eKale, Avinash\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cp\u003eThis book discusses in detail the structural, evolutionary and functional role of actin and its regulatory proteins in gliding motility in apicomplexan organisms, a unique phenomenon found in actin-myosin cytoskeletal elements.\u003c\/p\u003e\n\n\u003cp\u003eThe book also explores the potential of different actin regulators, namely formin, profilin, actin depolymerization factor (ADF), capping proteins (CPα and CPβ), cyclase-associated protein (CAP) and coronin 13–24 as potential drug targets against malaria.  As the chief components of the gliding motor, the actin-regulator proteins are characterized by unique features that make them promising targets for structure-based drug design.\u003c\/p\u003e\n\n\u003cp\u003eLastly, the book proposes a mathematical model, based on kinetic data mining, to help understand the most vital regulators for actin polymerization dynamics. \u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 2020-11-26\u003c\/p\u003e \u003cp\u003eFormat: Paperback\u003c\/p\u003e \u003cp\u003eISBN-13: 9789811374524\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-981-13-7450-0\u003c\/p\u003e \u003cp\u003eDimensions: 235cm x155cm\u003c\/p\u003e \u003cp\u003ePages: 101\u003c\/p\u003e ","brand":"Springer Nature Singapore","offers":[{"title":"Default Title","offer_id":44809529950348,"sku":"9789811374524","price":98.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9789811374524.jpg?v=1776036534","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9789811374524","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}