{"product_id":"9789401776356","title":"Focus on Structural Biology","description":"\u003ch1\u003eFocus on Structural Biology\u003c\/h1\u003e \u003ch2\u003eBecker, Oren M.; Karplus, Martin\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cp\u003eMolecular dynamics simulations have become instrumental in replacing our view of proteins as relatively rigid structures with the realization that they were dynamic systems, whose internal motions play a functional role. Over the years, such simulations have become a central part of biophysics. Applications of molecular dynamics in biophysics range over many areas. They are used in the structure determination of macromolecules with x-ray and NMR data, the modelling of unknown structures from their sequence, the study of enzyme mechanisms, the estimation of ligand-binding free energies, the evaluation of the role of conformational change in protein function, and drug design for targets of known structures. \u003c\/p\u003e\n\u003cp\u003eThe widespread application of molecular dynamics and related methodologies suggests that it would be useful to have available an introductory self-contained course by which students with a relatively limited background in chemistry, biology and computer literacy, can learn the fundamentals of the field. This \u003cstrong\u003eGuide to Biomolecular Simulations \u003c\/strong\u003etries to fill this need. The \u003cstrong\u003eGuide\u003c\/strong\u003e consists of six chapters which provide the fundamentals of the field and six chapters which introduce the reader to more specialized but important applications of the methodology. \u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 2016-08-23\u003c\/p\u003e \u003cp\u003eFormat: Paperback\u003c\/p\u003e \u003cp\u003eISBN-13: 9789401776356\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/1-4020-3587-X\u003c\/p\u003e \u003cp\u003eDimensions: 235cm x155cm\u003c\/p\u003e \u003cp\u003ePages: 203\u003c\/p\u003e ","brand":"Springer Netherlands","offers":[{"title":"Default Title","offer_id":44541657317516,"sku":"9789401776356","price":125.1,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9789401776356.jpg?v=1779043721","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9789401776356","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}