{"product_id":"9789401047562","title":"Medical Science Symposia Series: Pharmacology and Clinical Research","description":"\u003ch1\u003eMedical Science Symposia Series: Pharmacology and Clinical Research\u003c\/h1\u003e \u003ch2\u003eGodfraind, T.; Govoni, S.; Paoletti, Rodolfo; Vanhoutte, Paul M.\u003c\/h2\u003e \u003cp\u003eAlthough the importance of calcium (Ca\u003csup\u003e2+\u003c\/sup\u003e) in the  maintenance of cardiac contractility was recognized as early as 1880,  the critical role of the ion in the contractile process in skeletal,  cardiac, and smooth muscle has only been established within the last  three decades.\u003cbr\u003e  As the complexity of the pharmacological actions of the Ca\u003csup\u003e2+\u003c\/sup\u003e  channel inhibitors grows, there is a continued need to further clarify  the inhibitors, both chemically and functionally.\u003cbr\u003e  This volume provides an update of the field based on the work  presented at the 5th International Symposium on \u003cem\u003eCalcium  Antagonists:\u003c\/em\u003e \u003cem\u003ePharmacology and Clinical Research\u003c\/em\u003e. It reviews  the current state of the growing area of molecular biology of  Ca\u003csup\u003e2+\u003c\/sup\u003e channels. In the cardiovascular area, in addition to the  well-established clinical uses of Ca\u003csup\u003e2+\u003c\/sup\u003e channel inhibitors,  exciting new work pointing to an application in atherosclerosis is  described. The book also includes important uses of Ca\u003csup\u003e2+\u003c\/sup\u003e  antagonists in novel areas of interest such as the gastrointestinal  tract, renal protection and multi-drug resistance.\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 2013-01-22\u003c\/p\u003e \u003cp\u003eFormat: Paperback\u003c\/p\u003e \u003cp\u003eISBN-13: 9789401047562\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-94-011-1725-8\u003c\/p\u003e \u003cp\u003eDimensions: 240cm x160cm\u003c\/p\u003e \u003cp\u003ePages: 381\u003c\/p\u003e ","brand":"Springer Netherlands","offers":[{"title":"Default Title","offer_id":44398664286348,"sku":"9789401047562","price":49.49,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9789401047562.jpg?v=1775754714","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9789401047562","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}