{"product_id":"9789401043557","title":"Multiple Drug Resistance in Cancer: Cellular, Molecular and Clinical Approaches","description":"\u003ch1\u003eMultiple Drug Resistance in Cancer: Cellular, Molecular and Clinical Approaches\u003c\/h1\u003e \u003ch2\u003eClynes, Martin\u003c\/h2\u003e \u003cp\u003eThis book is an up-to-date review of current knowledge in the  field of multiple drug resistance in human cancer. The literature up  to the middle of 1993 is surveyed in specialist chapters written by  different experts. Topics covered include the molecular genetics,  cytogenetics and biochemistry of the  \u003cem\u003emdr\u003c\/em\u003e genes and  P-glycoprotein; alternative transport proteins in MDR; topoisomerases  I and II; cytochrome p450-enzymes and glutathione-  \u003cem\u003eS\u003c\/em\u003e-transferases in MDR; cellular models for MDR in solid tumours  and haemopoietic tumours; immunochemical and molecular biological  techniques for detection of MDR-related gene expression; and clinical  and pharmacological strategies to circumvent resistance. The book  brings together a new combination of approaches to this serious  clinical problem. \u003cbr\u003e\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 2012-10-14\u003c\/p\u003e \u003cp\u003eFormat: Paperback\u003c\/p\u003e \u003cp\u003eISBN-13: 9789401043557\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-94-011-0826-3\u003c\/p\u003e \u003cp\u003eDimensions: 260.0cm x195.0cm\u003c\/p\u003e \u003cp\u003ePages: 393.0\u003c\/p\u003e ","brand":"Springer Netherlands","offers":[{"title":"Default Title","offer_id":44398794702988,"sku":"9789401043557","price":49.49,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9789401043557_bec94f71-2dd8-4b14-8fe1-6d6f97f4ea9c.jpg?v=1759295987","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9789401043557","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}