{"product_id":"9789400768659","title":"Evolution-adjusted Tumor Pathophysiology:: The Novel Language of Tumor Biology","description":"\u003ch1\u003eEvolution-adjusted Tumor Pathophysiology:: The Novel Language of Tumor Biology\u003c\/h1\u003e \u003ch2\u003eReichle, Albrecht\u003c\/h2\u003e \u003cp\u003eCombined modularized therapies for metastatic cancer are pointing to central problems of communication among ‘systems participators’. A communication theory explains 'social engineering', endogenously induced or by implementing non-normative boundary conditions. Evolution-adjusted tumor pathophysiology is borne by an evolution theory, which contrasts narrative evolution histories. The tool of rationalizations constituting the tumor's normativity (inflammation, immune response etc.) represents the non-genomic counterpart of the tumor genome and should be additionally assessed during tumor staging. Evolution-adjusted tumor pathophysiology allows implementing applied systems biology, a novel clinical and pharmaceutical technology for bioengineering tumor response and personalizing tumor therapy. Combined modularized therapy, evolution-adjusted tumor pathophysiology, and ‘universal’ biomarkers concertedly address genetically based tumor heterogeneity.\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 2013-07-11\u003c\/p\u003e \u003cp\u003eFormat: Hardcover\u003c\/p\u003e \u003cp\u003eISBN-13: 9789400768659\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-94-007-6866-6\u003c\/p\u003e \u003cp\u003eDimensions: 235.0cm x155.0cm\u003c\/p\u003e \u003cp\u003ePages: 453.0\u003c\/p\u003e ","brand":"Springer Netherlands","offers":[{"title":"Default Title","offer_id":44542682038412,"sku":"9789400768659","price":152.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9789400768659.jpg?v=1759329116","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9789400768659","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}