{"product_id":"9783709119433","title":"The Intervertebral Disc: Molecular and Structural Studies of the Disc in Health and Disease","description":"\u003ch1\u003eThe Intervertebral Disc: Molecular and Structural Studies of the Disc in Health and Disease\u003c\/h1\u003e \u003ch2\u003eShapiro, Irving M.; Risbud, Makarand V.\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cp\u003eThe intervertebral disc is a complex structure that separates opposing vertebrae, permits a wide range of motion, and accommodates high biomechanical forces. Disc degeneration leads to a loss of function and is often associated with excruciating pain.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eWritten by leading scientists and clinicians,  the first part of the book provides a review of the basic biology of the disc in health and disease. The second part considers strategies to mitigate the effects of disc degeneration and discusses the possibility of engineering replacement tissues. The final section is devoted to approaches to model normal development and elucidate the pathogenesis of degenerative disc disease using animal, organ and cell culture techniques.  \u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eThe book bridges the gap between the basic and clinical sciences; the target audience includes basic scientists, orthopaedists and neurologists, while at the same time appealing to the needs of  graduate students, medical students, interns and fellows.\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 2016-08-23\u003c\/p\u003e \u003cp\u003eFormat: Paperback\u003c\/p\u003e \u003cp\u003eISBN-13: 9783709119433\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-3-7091-1535-0\u003c\/p\u003e \u003cp\u003eDimensions: 279cm x210cm\u003c\/p\u003e \u003cp\u003ePages: 446\u003c\/p\u003e ","brand":"Springer Vienna","offers":[{"title":"Default Title","offer_id":44406567796876,"sku":"9783709119433","price":116.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9783709119433.jpg?v=1776700877","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9783709119433","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}