Bacterial Lipopolysaccharides: Structure, Chemical Synthesis, Biogenesis and Interaction with Host Cells

Knirel, Yuriy A.; Valvano, Miguel A.

The bacterial lipopolysaccharide also known as endotoxin is exhaustively covered in the present work. Central emphasis is placed upon the fine chemical structure of the lipopolysaccharide and its significance for understanding their activity and function. In particular, the role it plays in the interaction of bacteria with other biological systems is examined. New aspects of their physicochemical biology are introduced and updates to the current knowledge concerning the lipopolysaccharide are provided. This important class of biomolecules has recently attracted the attention of many investigators, in particular for understanding its involvement in innate immunity, toll-like receptor recognition and intracellular signaling.

Details

Published by: Springer

Publication Date: 2011-07-13

Format: Hardcover

ISBN-13: 9783709107324

DOI: 10.1007/978-3-7091-0733-1

Dimensions: 235cm x155cm

Pages: 440