{"product_id":"9783662220528","title":"Intracellular Signal Transduction: The JAK-STAT Pathway","description":"\u003ch1\u003eIntracellular Signal Transduction: The JAK-STAT Pathway\u003c\/h1\u003e \u003ch2\u003eWilks, Andrew F.; Harpur, Ailsa G.\u003c\/h2\u003e \u003cp\u003eThis book is the first one written about the JAK\/STAT pathway. The JAK (Janus Kinase) Protein tyrosine kinases are novel phosphotransferases absolutely required for cellular signalling downstream of non-catalytic cytokine receptors (amongst others). These molecules are components in pathways utilising the STAT (Signal Transducers and Activators of Transcription) transcription factors. The basic components of the JAK\/STAT pathway are covered in detail, and the centre piece of the book is a guided tour of the pathway itself. An interesting addition to the book is the chapter on the use of Drosophila melanogaster as a genetic system to probe the pathway at the whole organism level. The book is targeted to researchers who have an interest in intracellular signalling.\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 2013-11-13\u003c\/p\u003e \u003cp\u003eFormat: Paperback\u003c\/p\u003e \u003cp\u003e ISBN-10: 9783662220528\u003c\/p\u003e \u003cp\u003eISBN-13: 9783662220528\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-3-662-22050-4\u003c\/p\u003e \u003cp\u003eDimensions: 254cm x178cm\u003c\/p\u003e \u003cp\u003ePages: 209\u003c\/p\u003e ","brand":"Springer","offers":[{"title":"Default Title","offer_id":44359193297036,"sku":"9783662220528","price":99.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9783662220528_4f6712dd-7bc8-48a7-b761-cef629655aad.jpg?v=1755104526","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9783662220528","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}