Microbiology Monographs: Biology and Biotechnology

Tatsumi, Nami; Inui, Masayuki

Corynebacterium glutamicum was discovered in Japan in 1956 as a natural glutamate producer. Its “microbial factory” qualities, such as its physiological plasticity and robust catalytic functionalities, have since facilitated the development of efficient production processes for amino acids, nucleotides and vitamins.

This monograph illustrates how the information gleaned from complete genome sequencing allows the rational engineering of the entire cellular metabolism and how systems biology permits the further optimization of C. glutamicum as a biocatalyst. Aspects of gene regulation, metabolic pathways, sugar uptake, protein secretion, cell division and biorefinery applications highlight the enormous biotechnological and biorefinery potential.

Details

Published by: Springer

Publication Date: 2012-08-14

Format: Hardcover

ISBN-13: 9783642298561

DOI: 10.1007/978-3-642-29857-8

Dimensions: 235cm x155cm

Pages: 416