Current Topics in Microbiology and Immunology

Ahmed, Rafi; Honjo, Tasuku

Adaptive immune responses serve as a key defense mechanism for the control of infections in vertebrates. Immune responses must be of sufficient strength to contain invading pathogens, antigen specific responses require regulatory mechanisms to ensure termination or downmodulation to avoid excessive damage to the host tissue. For both branches of the adaptive immune system, regulatory molecules i.e. coreceptors and ligands have been identified that control the signaling cascades initiated by engagement of the T cell and B cell antigen receptors. This book describes biological functions as well as molecular mechanisms of these molecules.

Details

Published by: Springer

Publication Date: 2013-05-29

Format: Paperback

ISBN-13: 9783642267772

DOI: 10.1007/978-3-642-19545-7

Dimensions: 235cm x155cm

Pages: 152