{"product_id":"9783642267192","title":"Biology of Extracellular Matrix","description":"\u003ch1\u003eBiology of Extracellular Matrix\u003c\/h1\u003e \u003ch2\u003eMecham, Robert\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cp\u003eKnowledge of the extracellular matrix (ECM) is essential to understand cellular differentiation, tissue development, and tissue remodeling.\u003c\/p\u003e\u003cp\u003eThis volume of the series “Biology of Extracellular Matrix” provides a timely overview of the structure, regulation, and function of the major macromolecules that make up the extracellular matrix. It covers topics such as collagen types and assembly of collagen-containing suprastructures, basement membrane, fibronectin and other cell-adhesive glycoproteins, proteoglycans\u003cb\u003e, \u003c\/b\u003emicrofibrils, elastin, fibulins and matricellular proteins, such as thrombospondin. It also explores the concept that ECM components together with their cell surface receptors can be viewed as intricate nano-devices that allow cells to physically organize their 3-D-environment.  Further, the role of the ECM in human disease and pathogenesis is discussed as well as the use of model organisms in elucidating ECM function.\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 2013-04-21\u003c\/p\u003e \u003cp\u003eFormat: Paperback\u003c\/p\u003e \u003cp\u003eISBN-13: 9783642267192\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-3-642-16555-9\u003c\/p\u003e \u003cp\u003eDimensions: 235cm x155cm\u003c\/p\u003e \u003cp\u003ePages: 426\u003c\/p\u003e ","brand":"Springer Berlin Heidelberg","offers":[{"title":"Default Title","offer_id":45382880067724,"sku":"9783642267192","price":296.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9783642267192.jpg?v=1779052202","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9783642267192","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}