{"product_id":"9783527356812","title":"Concepts in Pharmacokinetics, Pharmacodynamics, and Drug-Drug Interactions","description":"\u003ch3\u003eMethods \u0026amp; Principles in Medicinal Chemistry\u003c\/h3\u003e\u003ch1\u003eConcepts in Pharmacokinetics, Pharmacodynamics, and Drug-Drug Interactions\u003c\/h1\u003e\u003ch3\u003eGian Peter Camenisch\u003c\/h3\u003e\u003cdiv\u003e\u003cb\u003eMedical \/ Pharmacology\u003c\/b\u003e\u003c\/div\u003e\u003cbr\u003e\u003cdiv\u003e\n\u003cp\u003e\u003cb\u003eUnified mechanistic treatment of PK, PD, and DDI concepts\u003c\/b\u003e \u003c\/p\u003e\n\u003cp\u003eConventional resources often present PK, PD, and DDI as separate domains, offering empirical relationships without detailing underlying assumptions. \u003ci\u003eConcepts in Pharmacokinetics, Pharmacodynamics, and Drug-Drug Interactions\u003c\/i\u003e unifies all three disciplines within a single volume, anchoring each in biophysical principles. Written by a pharmaceutical scientist, this work supports coherent, assumption-aware model development across the drug development value chain. \u003c\/p\u003e\n\u003cp\u003eThe content is structured into eight sections covering biophysical fundamentals, pharmacokinetic principles, absorption, distribution, elimination, pharmacokinetic forecasting, pharmacodynamic receptor binding and in vivo pharmacology, and mechanisms of drug–drug interactions involving both PK- and PD-based pathways. \u003c\/p\u003e\n\u003cp\u003e This structure clarifies interdependencies across domains that are often obscured in fragmented treatments, supporting more transparent pharmacological modeling.Key features include: \u003c\/p\u003e\n\u003cul\u003e \u003cli\u003eSystematic elucidation of simplifications and assumptions embedded in standard PK, PD, and DDI models used across the field\u003c\/li\u003e \u003cli\u003eMechanistic grounding in binding dynamics, mass transfer principles, and reaction kinetics that underpin quantitative pharmacology frameworks\u003c\/li\u003e \u003cli\u003eCross-disciplinary applicability spanning pharmaceutical sciences, clinical pharmacology, and regulatory modeling in diverse professional settings\u003c\/li\u003e \u003cli\u003eSupport for model-informed drug development through frameworks that enhance predictive accuracy and transparent decision-making throughout the pipeline\u003c\/li\u003e \u003cli\u003eIntegrated coverage eliminating the need to consult multiple separate references when developing or evaluating pharmacological models\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003ePharmaceutical scientists, clinical pharmacologists, regulatory modelers, and advanced graduate students working across DMPK disciplines will find this volume a substantive single-source reference. By unifying PK, PD, and DDI within a biophysical framework, it equips practitioners to build more robust and transparent pharmacological models.\u003c\/p\u003e\n\u003c\/div\u003e\u003cdiv\u003e  \u003cp\u003e\u003cb\u003eGian Peter Camenisch, PhD, \u003c\/b\u003eis a senior scientist with close to 30 years of pharmaceutical experience across multiple DMPK-related disciplines spanning discovery and early\/late development. He brings extensive expertise in managing internal and external interfaces in global environments, with proven success in matrix team management. \u003c\/p\u003e\n\u003c\/div\u003e\u003cbr\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublication Date: \u003c\/td\u003e\n\u003ctd\u003e02 March 2027\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublisher: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eImprint: \u003c\/td\u003e\n\u003ctd\u003eWiley-VCH\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eISBN-13: \u003c\/td\u003e\n\u003ctd\u003e9783527356812\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormat: \u003c\/td\u003e\n\u003ctd\u003eHardback\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePage Count: \u003c\/td\u003e\n\u003ctd\u003e560\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":51489756709004,"sku":"9783527356812","price":0.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9783527356812.jpg?v=1784253081","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9783527356812","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}