{"product_id":"9783527354672","title":"Excited State Dynamics in DNA and RNA Experimental and Computational Approaches on Triplet State","description":"\u003ch1\u003eExcited State Dynamics in DNA and RNA\u003c\/h1\u003e\u003ch2\u003eExperimental and Computational Approaches on Triplet State\u003c\/h2\u003e\u003ch3\u003eJinquan Chen\u003c\/h3\u003e\u003cdiv\u003e\u003cb\u003eScience \/ Life Sciences \/ Biochemistry\u003c\/b\u003e\u003c\/div\u003e\u003cbr\u003e\u003cdiv\u003e\n\u003cp\u003e\u003cb\u003ePresents comprehensive insights into triplet excited state dynamics of DNA and RNA across experiment and theory\u003c\/b\u003e \u003c\/p\u003e\n\u003cp\u003eUnderstanding the excited state dynamics of DNA and RNA is fundamental to addressing both the detrimental and beneficial consequences of UV light on biological systems. While the triplet excited state is a precursor to damaging pathways such as photodamage, mutation, and carcinogenesis, it also offers opportunities for developing targeted therapies through DNA-targeted photosensitizing drugs. Despite its dual role, no single resource has systematically synthesized the experimental and theoretical progress in this field. \u003c\/p\u003e\n\u003cp\u003e\u003ci\u003eExcited State Dynamics in DNA and RNA: Experimental and Computational Studies on the Triplet State\u003c\/i\u003e provides the first comprehensive overview of this rapidly growing interdisciplinary area, bridging photochemistry, photobiology, and photomedicine. Beginning with a historical overview of the field, the volume progresses to cover triplet dynamics in canonical and noncanonical nucleobases, triplet-mediated photochemistry, and drug-sensitized processes in DNA. Later chapters examine cutting-edge computational photobiology and quantum mechanical simulations, highlighting how molecular structure and environment influence excited state behaviors. \u003c\/p\u003e\n\u003cp\u003eOffering a holistic perspective on mechanisms underpinning UV-induced damage and therapeutic opportunities, \u003ci\u003eExcited State Dynamics in DNA and RNA: \u003c\/i\u003e \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e Integrates photochemistry, photobiology, and photomedicine into a unified resource\u003c\/li\u003e\n\u003cli\u003e Presents experimental findings alongside theoretical models\u003c\/li\u003e\n\u003cli\u003e Highlights experimental advances in spectroscopy and ultrafast dynamics\u003c\/li\u003e\n\u003cli\u003e Includes computational studies using \u003ci\u003eab initio\u003c\/i\u003e and surface-hopping dynamics simulations\u003c\/li\u003e\n\u003cli\u003e Addresses both canonical and epigenetically modified nucleobases.\u003c\/li\u003e\n\u003cli\u003e Explores implications for drug-sensitized DNA triplet states and photoactivated therapies.\u003c\/li\u003e\n\u003cli\u003e Synthesizes current research trends into a pedagogical framework accessible to non-specialists\u003c\/li\u003e\n\u003c\/ul\u003e \u003cp\u003e\u003ci\u003eExcited State Dynamics in DNA and RNA: Experimental and Computational Studies on the Triplet State\u003c\/i\u003e is an essential resource for graduate-level and advanced undergraduate courses in molecular biophysics, photochemistry, and chemical biology. It is also a key reference for researchers and professionals working in molecular biology, biophysics, medicinal chemistry, and photomedicine.\u003c\/p\u003e\n\u003c\/div\u003e\u003cdiv\u003e  \u003cp\u003e\u003ci\u003e\u003cb\u003eJinquan Chen, PhD,\u003c\/b\u003e is Full Professor, State Key Laboratory of Precision Spectroscopy, East China Normal University (ECNU), Shanghai, China. His research focuses on developing femtosecond time-resolved spectroscopy techniques to investigate excited state dynamics in biomolecules, with particular emphasis on the photophysics and photochemistry of epigenetic nucleic acids and their triplet excited states. He has published over 130 journal articles, serves on the Early Career Researcher Editorial Board of the \u003c\/i\u003eChinese Journal of Chemical Physics\u003ci\u003e, and is Vice-President of the Shanghai Biophysics Society.\u003c\/i\u003e \u003c\/p\u003e\n\u003c\/div\u003e\u003cbr\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublication Date: \u003c\/td\u003e\n\u003ctd\u003e11 May 2026\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublisher: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eImprint: \u003c\/td\u003e\n\u003ctd\u003eWiley-VCH\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eISBN-13: \u003c\/td\u003e\n\u003ctd\u003e9783527354672\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormat: \u003c\/td\u003e\n\u003ctd\u003eHardback\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePage Count: \u003c\/td\u003e\n\u003ctd\u003e256\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWeight (oz): \u003c\/td\u003e\n\u003ctd\u003e24.0\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":44796402434188,"sku":"9783527354672","price":160.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9783527354672_1f87520c-860c-4ade-91fb-65a7e0c82377.jpg?v=1780158895","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9783527354672","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}