Comprehensive, up-to-date, and user-centered one-stop reference on the principles and applications of Field-Flow Fractionation (FFF), a highly versatile separation technology

Field-Flow Fractionation: Principles and Applications offers a comprehensive and topical one-stop reference on Field-Flow Fractionation (FFF), an important separation technique which has been proven successful in the analysis of natural and engineered nanoparticles, pharmaceuticals, proteins, polymers, soils, and food.

After introductory chapters on theory, principles, and instrumentation, a tutorial-style user guide addresses typical users’ questions and problems. In the application part, the separation of all relevant particle classes is discussed by international experts.

Sample topics covered in Field-Flow Fractionation: Principles and Applications include:

• Historical perspectives of the technique, normal versus steric versus hyperlayer modes, retention resolution, and fractionation power
• FFF techniques, including flow (asymmetric, frit inlet, and outlet), sedimentation, thermal, electric, and other novel techniques such as 2D
• How to determine if FFF is the correct choice and if it is being implemented correctly, along with general optimization strategies including carrier fluid, calibration, and reproducibility
• Sample overloading and recovery, detector selection, troubleshooting, and performance of other fractionation techniques

Both beginners and experienced chemists and researchers can confidently rely on Field-Flow Fractionation: Principles and Applications to confirm their own understanding and to improve their FFF methods and interpretation of their results.

Céline Guéguen, PhD, is Full Professor of Chemistry at the Université de Sherbrooke, Québec, Canada.

Mohammed Baalousha, PhD, is Professor of Environmental Nanoscience and director of the Environmental Nanoscience & Analytics Laboratory at the University of South Carolina, Columbia, South Carolina, United States.

S. Kim R. Williams is a Professor of Chemistry at the Colorado School of Mines, Golden, Colorado, United States