{"product_id":"9783527329038","title":"Metabolism of Drugs and Other Xenobiotics","description":"\u003ch1\u003eMetabolism of Drugs and Other Xenobiotics\u003c\/h1\u003e\u003ch3\u003ePavel Anzenbacher | Ulrich M. Zanger\u003c\/h3\u003e\u003cdiv\u003e\u003cb\u003eMedical \/ Toxicology\u003c\/b\u003e\u003c\/div\u003e\u003cbr\u003e\u003cdiv\u003eA practice-oriented desktop reference for medical professionals, toxicologists and pharmaceutical researchers, this handbook provides\u003cbr\u003e systematic coverage of the metabolic pathways of all major classes of xenobiotics in the human body. The first part comprehensively reviews\u003cbr\u003e the main enzyme systems involved in biotransformation and how they are orchestrated in the body, while parts two to four cover the three\u003cbr\u003e main classes of xenobiotics: drugs, natural products, environmental pollutants. The part on drugs includes more than 300 substances from\u003cbr\u003e five major therapeutic groups (central nervous system, cardiovascular system, cancer, infection, and pain) as well as most drugs of abuse\u003cbr\u003e \u003cbr\u003e including nicotine, alcohol and \"designer\" drugs. Selected, well-documented case studies from the most important xenobiotics classes illustrate general principles of metabolism, making this equally useful for teaching courses on pharmacology, drug metabolism or molecular\u003cbr\u003e toxicology.\u003cbr\u003e Of particular interest, and unique to this volume is the inclusion of a wide range of additional xenobiotic compounds, including food supplements, herbal preparations, and agrochemicals.\u003c\/div\u003e\u003cdiv\u003e Pavel Anzenbacher heads the Department of Pharmacology at Palacky University, Olomouc (Czech Republic) and is vicepresident of the Czech Society of Clinical and Experimental Pharmacology and Toxicology. Having obtained his academic degrees from Charles University, Prague and from the Academy of Sciences of the Czech Republic he joined the Faculty of Medicine at Palacky University. His scientific contacts and stays have included e.g. the Princeton University, Vanderbilt University, Nashville, University of Connecticut, INSERM Montpellier, University of Lubeck, Technical University Berlin and Jagellonian University Cracow. Professor Anzenbacher has authored over 150 original scientific publications and has, among other honours, received the Fogarty Award of the USPHS.\u003cbr\u003e \u003cbr\u003e Ulrich M. Zanger is deputy head of the Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart (Germany). A chemist by training, he began to work on drug metabolism at the Biocenter of the University of Basel, Switzerland, where he obtained a PhD\u003cbr\u003e degree in biochemistry. He undertook postdoctoral studies at the Southwestern Medical Center at Dallas, Texas, before returning to Basel and later moving to Stuttgart. His major research interests are in human drug metabolizing cytochromes P450 and in basic and clinical aspects\u003cbr\u003e of pharmacogenetics\/genomics. Professor Zanger has authored more than 130 scientific articles and is lecturing in pharmacology and toxicology at the University of Tubingen.\u003c\/div\u003e\u003cbr\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublication Date: \u003c\/td\u003e\n\u003ctd\u003e05 June 2012\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublisher: \u003c\/td\u003e\n\u003ctd\u003eWiley\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eImprint: \u003c\/td\u003e\n\u003ctd\u003eWiley-VCH\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eISBN-13: \u003c\/td\u003e\n\u003ctd\u003e9783527329038\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormat: \u003c\/td\u003e\n\u003ctd\u003eHardback\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePage Count: \u003c\/td\u003e\n\u003ctd\u003e753\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWeight (oz): \u003c\/td\u003e\n\u003ctd\u003e52.64\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":44315041726604,"sku":"9783527329038","price":261.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9783527329038_b3553a01-1296-47e5-bd93-2f64e6fe5873.jpg?v=1780618359","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9783527329038","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}