{"product_id":"9783319903903","title":"SpringerBriefs in Systems Biology: Systematic Discovery of Novel Gene Expression Elements Using Bioinformatics and Computational Biology Approaches","description":"\u003ch1\u003eSpringerBriefs in Systems Biology: Systematic Discovery of Novel Gene Expression Elements Using Bioinformatics and Computational Biology Approaches\u003c\/h1\u003e \u003ch2\u003eKadkhodaei, Saeid; Golestan Hashemi, Farahnaz Sadat; Akhavan Rezaei, Morvarid; Abbasiliasi, Sahar; Tan, Joo Shun; Memari, Hamid Rajabi; Bande, Faruku; Baradaran, Ali; Moradpour, Mahdi; Ariff, Arbakariya B,\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cp\u003eThis book is a practical review which focuses on computational analysis and on \u003ci\u003ein silico\u003c\/i\u003e approaches towards the systematic discovery of various key functional gene expression elements in microalgae as a model. So far, in this regard very little information is available. Efficient stepwise procedures for analysing the matrix attachment regions (MARs) are outlined, as well as for translation initiation sites (TIS), signal peptide (SP) sequences, gene optimization and transformation systems. These outlines can be efficiently deployed as practical models for the systematic discovery of key expression elements and for the optimization of cis\/transgenes in other micro\/organisms. \u003c\/p\u003e  \u003cp\u003eThe first chapter is an introduction on the key gene expression elements analysed in this book, including scaffold\/matrix attachment regions, translation initiation sites, signal peptides as well as gene optimization. Chapter 2 focuses on systematic strategies and computational approaches toward \u003ci\u003ein silico \u003c\/i\u003eanalysis of each factor. The analyses outcomes is assessed individually in chapter 3 followed by developing the specific conceptual models for each element in Chapter 4. The concluding remarks are discussed in Chapter 5.\u003cb\u003e \u003c\/b\u003e\u003c\/p\u003e  \u003cp\u003eThis work is of interest to computational and experimental biologists interested in transcriptional regulation analysis as well as to researchers and scientists who wish to consider the use of bioinformatics and computational biology in design, analysis, or regulatory reviews of key gene expression elements for the production of recombinant proteins experiments.\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 2018-05-25\u003c\/p\u003e \u003cp\u003eFormat: Paperback\u003c\/p\u003e \u003cp\u003eISBN-13: 9783319903903\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-3-319-90391-0\u003c\/p\u003e \u003cp\u003eDimensions: 235cm x155cm\u003c\/p\u003e \u003cp\u003ePages: 120\u003c\/p\u003e ","brand":"Springer International Publishing","offers":[{"title":"Default Title","offer_id":44542662508684,"sku":"9783319903903","price":49.49,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9783319903903.jpg?v=1775823074","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9783319903903","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}