{"product_id":"9783319807584","title":"Springer Theses","description":"\u003ch1\u003eSpringer Theses\u003c\/h1\u003e \u003ch2\u003eFrega, Monica\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cp\u003eThe book\npresents a new, powerful model of neuronal networks, consisting of a\nthree-dimensional neuronal culture in which 3D neuronal networks are coupled to\nmicro-electrode-arrays (MEAs). It discusses the main advantages of the\nthree-dimensional system compared to its two-dimensional counterpart, and shows\nthat the network dynamics, recorded during both spontaneous and stimulated\nactivity, differs between the two models, with the 3D system being better able\nto emulate the \u003ci\u003ein vivo\u003c\/i\u003e behaviour of neural networks. The book offers an\nextensive analysis of the system, from the theoretical background, to its\ndesign and applications in neuro-pharmacological studies. Moreover, it\nincludes a concise yet comprehensive introduction to both 2D and 3D neuronal\nnetworks coupled to MEAs, and discusses the advantages, limitations and\nchallenges of their applications as cellular and tissue-like \u003ci\u003ein vitro\u003c\/i\u003e experimental model systems.\u003c\/p\u003e\n \n  \n  \n \n\n\n\u003cp\u003e\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 2018-04-25\u003c\/p\u003e \u003cp\u003eFormat: Paperback\u003c\/p\u003e \u003cp\u003eISBN-13: 9783319807584\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-3-319-30237-9\u003c\/p\u003e \u003cp\u003eDimensions: 235cm x155cm\u003c\/p\u003e \u003cp\u003ePages: 148\u003c\/p\u003e ","brand":"Springer International Publishing","offers":[{"title":"Default Title","offer_id":46266246365324,"sku":"9783319807584","price":98.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9783319807584.jpg?v=1770816781","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9783319807584","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}