{"product_id":"9783319475172","title":"The CAPRISA Clinical Trials: HIV Treatment and Prevention","description":"\u003ch1\u003eThe CAPRISA Clinical Trials: HIV Treatment and Prevention\u003c\/h1\u003e \u003ch2\u003eAbdool Karim, Quarraisha; Abdool Karim, Salim S.; Baxter, Cheryl\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cp\u003eSince its inception 14 years ago, CAPRISA has conducted numerous clinical studies that have influenced international TB-HIV treatment guidelines as well as HIV prevention through innovations in the microbicide and vaccine fields. This book provides a historical account of how each of CAPRISA’s high impact studies was created, developed, implemented, analysed and communicated.  In doing so, the reader is taken on a journey that provides glimpses into the genesis of research ideas and how this ultimately leads to a range of HIV prevention and treatment studies that have impacted the global response to the HIV and TB epidemics.\u003cbr\u003e\u003c\/p\u003e\u003cp\u003eComprised of 5 sections, the book details the following:\u003cbr\u003e\u003c\/p\u003e\u003col\u003e  \u003cli\u003eHIV epidemic in      South Africa and the establishment of a research centre to undertake      clinical, epidemiological and laboratory research on HIV.\u003ci\u003e\u003c\/i\u003e\n\u003c\/li\u003e  \u003cli\u003eCAPRISA’s clinical trials on HIV and HSV-2 prevention. These studies      investigated the impact of tenofovir gel as topical antiretroviral      pre-exposure prophylaxis (PrEP), implementation of topical PrEP through      family planning clinics, conditional cash incentives for HIV prevention,      HIV vaccines, and passive immunisation with broadly neutralising antibodies.      \u003ci\u003e\u003c\/i\u003e\n\u003c\/li\u003e  \u003cli\u003eCAPRISA’s research on the treatment of HIV and TB co-infection. \u003ci\u003e\u003c\/i\u003e\n\u003c\/li\u003e  \u003cli\u003eA review      of the major scientific findings from the CAPRISA studies on acute infection      and genital mucosal immunology.  \u003ci\u003e\u003c\/i\u003e\n\u003c\/li\u003e  \u003cli\u003eEssential      support activities for the conduct of clinical trials, including research laboratories and pharmacies, as well as      establishing effective communication and sustainable structures for      community engagement to maintain effective and respectful partnerships      with participating communities. The book concludes with a chapter about the      challenges facing future HIV prevention and treatment trials.\u003ci\u003e\u003c\/i\u003e\n\u003c\/li\u003e \u003c\/ol\u003e\u003cp\u003e\u003ci\u003eThe CAPRISA ClinicalTrials: HIV Treatment and Prevention\u003c\/i\u003e is a resource for undergraduate and postgraduate students, health care providers, doctors, decision-makers and researchers who are seeking guidance and insights on clinical trials – their creation, conduct and impact.\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 2017-01-26\u003c\/p\u003e \u003cp\u003eFormat: Hardcover\u003c\/p\u003e \u003cp\u003eISBN-13: 9783319475172\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-3-319-47518-9\u003c\/p\u003e \u003cp\u003eDimensions: 235cm x155cm\u003c\/p\u003e \u003cp\u003ePages: 243\u003c\/p\u003e ","brand":"Springer International Publishing","offers":[{"title":"Default Title","offer_id":44395556339852,"sku":"9783319475172","price":143.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9783319475172.jpg?v=1779585293","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9783319475172","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}