Recent Results in Cancer Research

Dietel, Manfred; Wittekind, Christian; Bussolati, Gianni; Winterfeld, Moritz

This book presents an overview of the most important current developments in the pre-analytical handling of tissue. It addresses in particular potential ways to improve the situation whereby methods employed in the pre-analytical phase – the period from surgical removal of tissue to the start of pathological processing – have remained essentially unchanged for decades with only modest standardization. It is examined how the pre-analytical period can be optimized, resulting not only in an increase in diagnostic quality but also in a reduction in processing time and costs. Among the key topics examined are the so-called cold ischemia time between tissue removal and fixation, the potential superiority of vacuum-based preservation over immediate formalin fixation, two-temperature fixation, molecular analysis methods, and the pre-analytics of specimens from particular tissues. Readers will find this book to be an important update that reveals the full importance of the pre-analytical phase for quality of pathological work-up.

Details

Published by: Springer

Publication Date: 2016-10-06

Format: Paperback

ISBN-13: 9783319349824

DOI: 10.1007/978-3-319-13957-9

Dimensions: 235cm x155cm

Pages: 133