{"product_id":"9783319328041","title":"Advances in Experimental Medicine and Biology: Prediction, Selection and Activity of Specific Inhibitors","description":"\u003ch1\u003eAdvances in Experimental Medicine and Biology: Prediction, Selection and Activity of Specific Inhibitors\u003c\/h1\u003e \u003ch2\u003eBöldicke, Thomas\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cp\u003eThis book presents an overview of the most relevant protein knockdown techniques. Readers will find a description of the generation and use of recombinant human antibodies, ER intrabodies and peptides as well as a description of the working mechanism and potential of the inhibitory action of each of these molecules. The book will also describe the selection and activity of a number of phosphatases, aptamers and allosteric modulators, focusing on A G protein coupled receptors. The book starts with a chapter on the \u003ci\u003ein silico\u003c\/i\u003e prediction of target-inhibitor interactions.\u003c\/p\u003e\u003cp\u003eKey aspects of this book are:\u003c\/p\u003e\u003cp\u003e- Selection strategies for monoclonal and recombinant human antibodies\u003ci\u003e\u003c\/i\u003e\u003c\/p\u003e\u003cp\u003e- Selection strategies for ER intrabodies, peptides and aptamers\u003ci\u003e\u003c\/i\u003e\u003c\/p\u003e- Examples of the most efficient inhibitors and their applications in protein biochemistry and cell biology\u003cp\u003e\u003c\/p\u003e\u003cp\u003e- Antibodies for cancer therapy and inhibitors of angiogenesis.\u003c\/p\u003e\u003cp\u003eThe book will be of great interest to scientists and students working in the life sciences on all areas related to protein biology. The variety of methods to modulate the activities of specific proteins which are introduced here will be of great benefit to the reader who is interested in general protein research or to readers who have very specific protein related questions.\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 2016-06-06\u003c\/p\u003e \u003cp\u003eFormat: Hardcover\u003c\/p\u003e \u003cp\u003eISBN-13: 9783319328041\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-3-319-32805-8\u003c\/p\u003e \u003cp\u003eDimensions: 235cm x155cm\u003c\/p\u003e \u003cp\u003ePages: 288\u003c\/p\u003e ","brand":"Springer International Publishing","offers":[{"title":"Default Title","offer_id":47978441015436,"sku":"9783319328041","price":152.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9783319328041.jpg?v=1777375103","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9783319328041","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}