{"product_id":"9783319305745","title":"Alternating Electric Fields Therapy in Oncology: A Practical Guide to Clinical Applications of Tumor Treating Fields","description":"\u003ch1\u003eAlternating Electric Fields Therapy in Oncology: A Practical Guide to Clinical Applications of Tumor Treating Fields\u003c\/h1\u003e \u003ch2\u003eWong, Eric T.\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cp\u003eThis concise text provides a\ncomplete overview of alternating electric fields therapy -- also known as tumor\ntreating fields -- for glioblastoma and other types of solid tumor\nmalignancies. Readers are given a fundamental understanding of this novel\nanti-cancer treatment modality by learning from clinical trial data as well as\nthe physical and cell biology effects on tumor cells when alternating electric\nfields are applied both \u003ci\u003ein vitro\u003c\/i\u003e and \u003ci\u003ein vivo\u003c\/i\u003e.\u003c\/p\u003e\n\n\u003cp\u003eChapters illustrate the physics\nbehind electric field propagation in space and other media. This is\nfollowed by a review of our current understanding of the electric field effects\non dividing cells - including the disruption of cytokinesis, proper chromosome\nsegregation and activation on the cell surface chaperons that induce\nimmunogenic cell death. Data from phase III trials for the treatment of\nrecurrent and newly diagnosed glioblastomas are included, as well as some of\nthe ancillary \u003ci\u003epost hoc\u003c\/i\u003e analyses thatwere performed by various\ninvestigators. The remainder of the chapter covers other solid tumor\nmalignancies, including non-small cell lung cancer, pancreatic cancer and\novarian cancer, as this treatment modality is being applied to systemic\nmalignancies.\u003c\/p\u003e\n\n\u003cp\u003e\u003ci\u003eAlternating Electric Fields\nTherapy in Oncology\u003c\/i\u003e offers oncologists,\nneurologists, radiation oncologists, biomedical engineers, cell biologists and\nmitosis researchers the fundamentals needed for clinical practice.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 2016-11-02\u003c\/p\u003e \u003cp\u003eFormat: Hardcover\u003c\/p\u003e \u003cp\u003eISBN-13: 9783319305745\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-3-319-30576-9\u003c\/p\u003e \u003cp\u003eDimensions: 235cm x155cm\u003c\/p\u003e \u003cp\u003ePages: 129\u003c\/p\u003e ","brand":"Springer International Publishing","offers":[{"title":"Default Title","offer_id":44395502043276,"sku":"9783319305745","price":89.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9783319305745.jpg?v=1772933806","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9783319305745","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}