{"product_id":"9783319149134","title":"SpringerBriefs in Computer Science: Using MRFalign","description":"\u003ch1\u003eSpringerBriefs in Computer Science: Using MRFalign\u003c\/h1\u003e \u003ch2\u003eXu, Jinbo; Wang, Sheng; Ma, Jianzhu\u003c\/h2\u003e \u003cp\u003eThis work covers sequence-based protein homology detection, a fundamental and challenging bioinformatics problem with a variety of real-world applications. The text first surveys a few popular homology detection methods, such as Position-Specific Scoring Matrix (PSSM) and Hidden Markov Model (HMM) based methods, and then describes a novel Markov Random Fields (MRF) based method developed by the authors. MRF-based methods are much more sensitive than HMM- and PSSM-based methods for remote homolog detection and fold recognition, as MRFs can model long-range residue-residue interaction. The text also describes the installation, usage and result interpretation of programs implementing the MRF-based method.\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 2015-03-03\u003c\/p\u003e \u003cp\u003eFormat: Paperback\u003c\/p\u003e \u003cp\u003eISBN-13: 9783319149134\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-3-319-14914-1\u003c\/p\u003e \u003cp\u003eDimensions: 235cm x155cm\u003c\/p\u003e \u003cp\u003ePages: 51\u003c\/p\u003e ","brand":"Springer International Publishing","offers":[{"title":"Default Title","offer_id":45548511035532,"sku":"9783319149134","price":49.49,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9783319149134.jpg?v=1772897649","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9783319149134","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}