{"product_id":"9783034877831","title":"Experientia Supplementum","description":"\u003ch1\u003eExperientia Supplementum\u003c\/h1\u003e \u003ch2\u003eScherer, Gerd; Schmid, Michael\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cp\u003eFollowing an opening chapter by the late Susumu Ohno on paralogues of sex-determining genes, the five best-studied genes essential for early mammalian gonadal development are portrayed in detail: SF-1 and WT1 and their roles in early events in gonadal development, SRY and SOX9 in testis determination, and the anti-testis gene DAX-1. Subsequent chapters look at the roles of these genes in sex determination in marsupial mammals, birds, reptiles, amphibians and fish, and review the different sex-determining mechanisms, genetic and environmental, that operate in these different vertebrate classes. Two insights emerge: one, that the same basic set of genes appears to operate during early gonadal development in all vertebrates, despite the differences in mechanisms; the other, that sex determination in vertebrates results from a complex network of regulatory interactions and not from a simple hierarchical cascade of gene actions.\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Birkhäuser\u003c\/p\u003e \u003cp\u003ePublication Date: 2013-10-03\u003c\/p\u003e \u003cp\u003eFormat: Paperback\u003c\/p\u003e \u003cp\u003eISBN-13: 9783034877831\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-3-0348-7781-7\u003c\/p\u003e \u003cp\u003eDimensions: 244cm x170cm\u003c\/p\u003e \u003cp\u003ePages: 205\u003c\/p\u003e ","brand":"Birkhäuser Basel","offers":[{"title":"Default Title","offer_id":45548470796428,"sku":"9783034877831","price":49.49,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9783034877831.jpg?v=1774496002","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9783034877831","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}