{"product_id":"9783034806787","title":"SpringerBriefs in Biochemistry and Molecular Biology: Regulation of Eukaryotic Gene Expression","description":"\u003ch1\u003eSpringerBriefs in Biochemistry and Molecular Biology: Regulation of Eukaryotic Gene Expression\u003c\/h1\u003e \u003ch2\u003eBarrett, Lucy W.; Fletcher, Sue; Wilton, Steve D.\u003c\/h2\u003e \u003cp\u003eThere is now compelling evidence that the complexity of higher organisms correlates with the relative amount of non-coding RNA rather than the number of protein-coding genes. Previously dismissed as “junk DNA”, it is the non-coding regions of the genome that are responsible for regulation, facilitating complex temporal and spatial gene expression through the combinatorial effect of numerous mechanisms and interactions working together to fine-tune gene expression. The major regions involved in regulation of a particular gene are the 5’ and 3’ untranslated regions and introns. In addition, pervasive transcription of complex genomes produces a variety of non-coding transcripts that interact with these regions and contribute to regulation. This book discusses recent insights into the regulatory roles of the untranslated gene regions and non-coding RNAs in the control of complex gene expression, as well as the implications of this in terms of organism complexity and evolution.​\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 2013-07-09\u003c\/p\u003e \u003cp\u003eFormat: Paperback\u003c\/p\u003e \u003cp\u003eISBN-13: 9783034806787\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-3-0348-0679-4\u003c\/p\u003e \u003cp\u003eDimensions: 235cm x155cm\u003c\/p\u003e \u003cp\u003ePages: 56\u003c\/p\u003e ","brand":"Springer Basel","offers":[{"title":"Default Title","offer_id":47673417367692,"sku":"9783034806787","price":49.49,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9783034806787.jpg?v=1776527784","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9783034806787","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}