Neuroimmunology, 2nd Edition offers a practical, clinically focused guide to the ever evolving field of neuroinflammatory disease. Covering multiple sclerosis, autoimmune neurology, immune-mediated disorders of the central and peripheral nervous systems, and systemic autoimmune and inflammatory conditions affecting neurological function, this comprehensive resource integrates current scientific understanding with real-world clinical practice. Foundational chapters on immunology, neuroimaging, antibody testing, and immunotherapy provide the essential framework for understanding disease mechanisms and management.

Written by internationally recognized experts, the book examines the clinical presentation, diagnosis, pathophysiology, and treatment of a broad spectrum of neuroimmune disorders, including multiple sclerosis, autoimmune encephalitis, neuromyelitis optica spectrum disease (NMOSD), MOG antibody–associated disease (MOGAD), stiff person syndrome, myasthenia gravis, inflammatory neuropathies, vasculitis, neurosarcoidosis, and more. This fully updated second edition features expanded coverage of newly established international diagnostic criteria for MS and MOGAD, infectious and oncologic mimics of inflammatory disease, complications of immunotherapies, immune checkpoint inhibitor–associated neurotoxicity, vaccinations in immunocompromised patients, and pregnancy and breastfeeding management in multiple sclerosis.

Organized around both disease-specific topics and symptom-based clinical approaches, Neuroimmunology, 2nd Edition delivers clear clinical reasoning and practical guidance for everyday patient care. An invaluable reference for neurologists, residents, fellows, and other clinicians, it provides an authoritative and up-to-date overview of the full spectrum of autoimmune neurology and neuroimmunology.

Amanda L. Piquet, MD

University of Colorado Anschutz

School of Medicine

Aurora, CO

USA

Enrique Alvarez MD, PhD

University of Colorado Anschutz

School of Medicine

Aurora, CO

USA