Oscillatory Life Mechanisms and Functions of Biological Rhythms

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Lecture Notes on Mathematical Modelling in the Life Sciences

Oscillatory Life

Mechanisms and Functions of Biological Rhythms

Albert Goldbeter

Mathematics / Applied

Heartbeat, breathing, alternating periods of waking and sleeping, the ovarian cycle, animal migration, plant flowering: life is rhythm. Numerous other periodic processes are engaged in cell life, often imperceptibly. For example, a biological clock controls the cycles of cellular division, from the earliest embryonic phases to the adult organism. Brain activity is underpinned by neuronal rhythms, and many hormones are secreted in a pulsatile manner.

Among the many rhythms that regulate organisms and their physiology, some are linked to the environment: circadian rhythms, which roughly follow a 24-hour pattern, allow us to adapt to alternating night-and-day cycles; other rhythms are linked to the yearly seasonal cycle: flowering, hibernation, migrations, and reproduction in numerous species. Life rhythms can vary from a fraction of a second to several decades.

Where do these multiple rhythms come from? What functions do they serve? Why are periodic phenomena so common among biological systems?

This book aims to present the main life rhythms and to delve into the heart of the underlying regulatory mechanisms.

A thorough review of all the mechanisms that regulate the principal life rhythms. In a jargon-free style this book examines the origin of various types of oscillation and shows what unites them, beyond their specific mechanisms.

This book offers the first synthesis of existing knowledge on the rhythms of life, as observed at different levels of biological organisation. Based on experiential data and on modelling techniques, the author highlights the origin and dynamic rhythms that constitute an essential aspect of existence: oscillating life.

Albert Goldbeter is an Honorary Professor in the Faculty of Sciences at Université Libre de Bruxelles (ULB), Brussels, Belgium. His research pertains primarily to modeling the moldecular mechanism of a variety of cellular rhythms. He is the author of several books: “Rythmes et chaos dans les systèmes biochimiques et cellulaires” (Masson, Paris, 1990), “Biochemical Oscillations and Cellular Rhythms. The molecular bases of Periodic and Chaotic Behaviour” (Cambridge Univ. Press, Cambridge, UK, 1996), and “La Vie oscillatoire. Au cœur des rythmes du vivant” (Odile Jacob, Paris, 2010), a revised and augmented version of which was published in April 2018 under the title: “Au cœur des rythmes du vivant. La Vie oscillatoire” (Odile Jacob, Paris).

For his pioneering work on the mathematical modeling of biological processes he received in 2010 the Quinquennial Prize for Exact Fundamental Sciences from the Belgian Science Foundation (FNRS).


Publication Date: 11 February 2027
Publisher: Springer Nature Switzerland
Imprint: Springer
ISBN-13: 9783032373885
Format: Hardback
Page Count: 327

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