{"product_id":"9783032343307","title":"Sulforaphane in Human Health Molecular Mechanisms, Pharmacokinetics, and Therapeutic Potential","description":"\u003ch3\u003eSpringerBriefs in Food, Health, and Nutrition\u003c\/h3\u003e\u003ch1\u003eSulforaphane in Human Health\u003c\/h1\u003e\u003ch2\u003eMolecular Mechanisms, Pharmacokinetics, and Therapeutic Potential\u003c\/h2\u003e\u003ch3\u003eKalina Sikorska-Zimny\u003c\/h3\u003e\u003cdiv\u003e\u003cb\u003eMedical \/ Nutrition\u003c\/b\u003e\u003c\/div\u003e\u003cbr\u003e\u003cdiv\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan lang=\"EN-US\" style=\"mso-ansi-language: EN-US;\"\u003eThis concise research overview examines sulforaphane, a bioactive isothiocyanate that has become a central focus in nutritional biochemistry, molecular pharmacology, and translational health science. Bringing together evidence from plant biology, enzymology, human metabolism, and clinical research, it traces the compound’s pathway from its glucosinolate precursor in Brassicaceae vegetables to its biologically active forms in humans. The book integrates current knowledge on chemical properties, biosynthesis, myrosinase\u003c\/span\u003e\u003cspan lang=\"EN-US\" style=\"font-family: 'Cambria Math',serif; mso-bidi-font-family: 'Cambria Math'; mso-ansi-language: EN-US;\"\u003e‑\u003c\/span\u003e\u003cspan lang=\"EN-US\" style=\"mso-ansi-language: EN-US;\"\u003emediated hydrolysis, and the factors influencing bioavailability, stability, and metabolic variability.\u003c\/span\u003e\u003c\/p\u003e\r\n\u003cp class=\"MsoNormal\"\u003e\u003cspan lang=\"EN-US\" style=\"mso-ansi-language: EN-US;\"\u003eThrough a critical synthesis of experimental, molecular, and clinical findings, the volume explains how sulforaphane modulates pathways relevant to detoxification, oxidative stress, inflammation, epigenetic regulation, and pharmacokinetics. Coverage of preclinical and human studies outlines therapeutic potential in oncology, neurodegeneration, cardiometabolic disorders, and immune modulation, while also addressing limitations in clinical translation, formulation challenges, and interindividual differences in response.\u003c\/span\u003e\u003c\/p\u003e\r\n\u003cp class=\"MsoNormal\"\u003e\u003cspan lang=\"EN-US\" style=\"mso-ansi-language: EN-US;\"\u003eBy combining foundational biochemical insights with emerging biomedical applications, the book provides an integrated resource for researchers and professionals in nutrition science, pharmacology, toxicology, functional foods, and translational medicine seeking an authoritative and balanced synthesis of current evidence.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\u003cdiv\u003e\u003cp class=\"MsoNormal\"\u003e\u003cspan lang=\"EN-US\" style=\"mso-ansi-language: EN-US;\"\u003ePharmD, MSc Eng. Kalina Sikorska-Zimny is a food scientist with over 20 years of experience in food chemistry, functional foods, and bioactive plant compounds. Since 2005, her research has focused on health-promoting components of vegetables, particularly Brassicaceae species. She has conducted analytical and experimental studies on glucosinolates and their bioactive derivatives, including sulforaphane and indole-3-carbinol, with special emphasis on their biosynthesis, bioavailability, and health effects. She is the author or co-author of more than 27 scientific publications, including highly cited reviews in Critical Reviews in Food Science and Nutrition (2020) and Nutrients (2021) addressing glucosinolate metabolism and interaction with the human gut microbiota. Her work has been presented at numerous international events, including conferences, invited lectures and academic talks delivered abroad. She serves as a peer reviewer for several leading international journals in the fields of food science, nutrition, and pharmacology. Dr. Sikorska-Zimny has over 15 years of academic teaching experience and is one of two authors of a biochemistry course manual for medical and health-science students.\u003c\/span\u003e\u003c\/p\u003e\u003c\/div\u003e\u003cbr\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublication Date: \u003c\/td\u003e\n\u003ctd\u003e18 September 2026\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublisher: \u003c\/td\u003e\n\u003ctd\u003eSpringer Nature Switzerland\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eImprint: \u003c\/td\u003e\n\u003ctd\u003eSpringer\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eISBN-13: \u003c\/td\u003e\n\u003ctd\u003e9783032343307\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormat: \u003c\/td\u003e\n\u003ctd\u003ePaperback \/ softback\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e","brand":"Springer Nature Switzerland","offers":[{"title":"Default Title","offer_id":51217848303756,"sku":"9783032343307","price":44.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9783032343307.jpg?v=1783019243","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9783032343307","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}