Advances in pediatric endocrinology are reshaping how clinicians understand, diagnose, and treat short stature, and this volume brings those breakthroughs into sharp focus. Blending foundational science with emerging therapeutic strategies, it offers a comprehensive and clinically actionable guide for practitioners committed to improving growth outcomes in children.

The book moves through a wide spectrum of contemporary issues, beginning with innovative non‑hGH therapies and the transformative role of artificial intelligence in growth‑disorder management. It challenges long‑standing assumptions by deconstructing the category of idiopathic short stature and provides nuanced analysis of the strengths and limitations of growth hormone stimulation testing. Readers are guided through evolving concepts of growth hormone deficiency, the unique growth trajectories of children born small for gestational age, and the expanding therapeutic landscape shaped by long‑acting growth hormone formulations. Further chapters illuminate the complexities of imprinting disorders and their diagnostic pathways, while also examining the evidence‑based use of GnRH analogues and aromatase inhibitors as adjunctive therapies during puberty. Together, these discussions create a cohesive, forward‑looking exploration of the future of growth‑disorder care.

Written for pediatric endocrinologists, general pediatricians, fellows, and researchers, Pediatric Growth Disorders: Controversies in Diagnosis and Management provides the scientific depth, diagnostic clarity, and therapeutic insight needed to navigate an era in which precision medicine and technological innovation are redefining what is possible for children with short stature.

Robert Rapaport is Professor of Pediatrics in the Division of Pediatric Endocrinology and Diabetes in the Jack and Lucy Clark Department of Pediatrics at the Icahn School of Medicine at Mount Sinai and Mount Sinai Kravis Children’s Hospital. He is also the Emma Elizabeth Sullivan Professor of Pediatric Endocrinology and Diabetes and the Director of the Growth Center. Dr. Rapaport received his medical degree from State University of New York - Downstate Medical Center, training in Pediatrics at Schneider's Children's Hospital (Long Island Jewish Hospital - Hillside Medical Center) and his fellowship training in Pediatric Endocrinology at St. Christopher's Hospital for Children, Philadelphia and New York Hospital-Cornell Medical Center, New York. He has published numerous articles and chapters including chapters in major Pediatric (Nelson) and Pediatric Endocrinology (Sperling, Lifshitz and Pescovitz) textbooks.  Dr. Rapaport’s current research interests include growth and growth hormone in children born SGA, neonatal thyroid disease, growth hormone-immune interactions, aspects of childhood diabetes and pubertal disorders.

Martin O. Savage was Emeritus Professor of Paediatric Endocrinology at William Harvey Research Institute, Barts and the London School of Medicine & Dentistry, Queen Mary, University of London. He was head of the Paediatric Endocrine Unit at Barts and the London School of Medicine from 1982 to 2007. He has interests in growth disorders, specifically those with abnormalities in the GH-IGF-1 axis and in phenotype-genotype relationships of GH-IGF-1 axis defects, notably GH resistance. He published the first human case of an IGF-1 gene defect in the New England Journal of Medicine in 1996.  His other interests are Cushing’s syndrome and growth in chronic inflammatory diseases. He was General Secretary of the European Society for Paediatric Endocrinology (ESPE) from 1997 to 2004. He has lectured in 61 countries and has published 472 original articles, reviews, textbook chapters and books. In 2007, he was awarded the ESPE Andrea Prader Prize for contributions to paediatric endocrinology and in 2018 he received a Visionary Award from the American Human Growth Foundation. In 2022, he received a Research Excellence Award from the Dr Sulaiman Al Habib Medical Journal in Riyadh, and the British Society of Paediatric Endocrinology & Diabetes James M. Tanner Lifetime Achievement Award. He continues to lecture nationally and internationally.