Hypertension, the leading modifiable cause of premature death, affects the great majority of patients with chronic kidney disease (CKD).  The book will cover the epidemiology of CKD and hypertension and provide  an in-depth review of pathophysiological mechanisms linking these conditions, as well as the implications of this association in terms of cardiovascular risk. The reader will also find up-to-date evidence and guidelines for the screening, diagnosis and real-life management of patients with hypertension and chronic kidney disease and more importantly data and critical assessment of latest trials with new disease modifying treatment.

Among the topic covered in the book: the usefulness of out of office BP measurement, the role of albuminuria as a marker of risk and as a therapeutic target, the role of serum uric acid and salt intake in the prognosis and clinical management of CKD patients. The expanding therapeutic armamentarium to prevent hypertensive renal damage in diabetic and non diabetic patients will be reviewed, RAAS Is, SGLT2 is, drugs modulating aldosterone pathway  as well as new antihyperglycemic drugs. A chapter will cover resistant hypertension and its treatment by drugs and the use of renal denervation for CV and renal protection. Furthermore, updates on renovascular hypertension and preeclampsia will be provided. 

This book is a useful tool for clinicians but also to the research community interested in CKD and hypertension related renal damage who want to be up-to-date with the many new developments in the field.

Pantelis Sarafidis is Professor of Nephrology at the Aristotle University of Thessaloniki and Chair of the University Department of Nephrology in Hippokration Hospital of the same city. He also is the Head of the ESH Hypertension Excellence Center in this hospital. He is past Chair of the Hypertension and the Kidney Working Group of the European Society of Hypertension and past Chair of the European Renal Best Practice board of the European Renal Association. His clinical and research activities are focused on hypertension, diabetic and hypertensive nephropathy, cardiovascular disease in patients with chronic kidney disease and others. He has authored more than 450 articles in peer-reviewed international medical journals, and performed more than 300 lectures in national and international meetings in the areas of Nephrology, Hypertension and related fields.

Roberto Pontremoli is Full Professor of Medicine at the Dept of Internal Medicine, University of Genoa Medical School, chief of 2nd Medical Clinic and Head of Hypertension Unit at IRCCS Ospedale Policlinico San Martino in Genoa (Italy). He has a long-standing experience as a clinical investigator in the field of renal and cardiovascular medicine. A European Society of Hypertension (ESH) Specialist and former member of the Directory Board of Italian Society of Hypertension, he is also President of the Italian Society of Nephro-Cardiology (SINCAR). Dr Pontremoli is Associate Editor of Internal and Emergency Medicine, European Journal of Internal Medicine, Journal of Nephrology and Clinical Kidney Journal. Dr. Pontremoli’s research interests cover cardio-renal interactions in hypertension, albuminuria as a cardiovascular and renal risk marker and diabetic nephropathy. He has contributed over 300 PudMed indexed publications in peer reviewed journals and has an Hirsh Index of 49.