This book is written in a question-and-answer (Q&A) format and is designed to provide a comprehensive and yet concise state-of-the-art overview of the major issues specific to the field of immunohistochemistry. It also serves as an informative and user-friendly reference for information related to using the most up-to-date immunohistochemistry, in situ hybridization, and molecular oncologic pathology in clinical diagnosis. This book improves upon the previous editions by incorporating significant revisions throughout and new additions. Key features and changes in this edition include new chapters on molecular oncologic pathology, over 100 new questions and answers, more refined working antibody panels, and more diagnostic and predictive biomarkers. High-quality color images are also incorporated throughout the book, making it a valuable visual resource. Many chapters have been significantly revised and updated to include relevant new questions, new markers, more refined IHC panels, representative pictures, and current references. There are also many comparisons of data from Geisinger Medical Laboratories to data from the literature, which continue to be a unique feature in this book. The updated Appendix contains detailed antibody information for automated immunostaining procedures for near 250 antibodies.

Written by an international group of experts in the field, Handbook of Practical Immunohistochemistry: Frequently Asked Questions 4th Edition serves as an extensive and practical guide for surgical pathologists, pathology residents and fellows, cytopathologists, and cytotechnologists.

Fan Lin
Department of Laboratory Medicine
Geisinger Health System
Danville, PA
USA

Jeffrey W. Prichard
Department of Laboratory Medicine
Geisinger Medical Center
Danville, PA
USA

Haiyan Liu
Department of Laboratory Medicine
Geisinger Medical Center
Danville, PA
USA

Myra L. Wilkerson
Department of Laboratory Medicine
Geisinger Medical Center
Danville, PA
USA

Yi Ding
Department of Laboratory Medicine
Geisinger Medical Center
Danville, PA 
USA