{"product_id":"9783031395604","title":"Neuraxial Therapeutics A Comprehensive Guide","description":"\u003ch1\u003eNeuraxial Therapeutics\u003c\/h1\u003e\u003ch2\u003eA Comprehensive Guide\u003c\/h2\u003e\u003ch3\u003eTony Yaksh | Salim Hayek\u003c\/h3\u003e\u003cdiv\u003e\u003cb\u003eMedical \/ Pain Management\u003c\/b\u003e\u003c\/div\u003e\u003cbr\u003e\u003cdiv\u003e\n\u003cp\u003eThis book is a comprehensive reference of the neuraxial route for the delivery of therapeutics.  It reviews the historical evolution of this approach from its inception in the later 1800's to present day.   This amply referenced text covers basic discussions of spinal anatomy, embryogenesis,  neuraxial vascularity,  cerebrospinal fluid flow dynamics and parenchymal molecule movement. The pharmacokinetic and pharmacodynamic properties of  different intrathecal agents are explored in detail with particular reference to clinical correlates  in pain and spasticity.   Particular attention is paid to the issues relevant to preclinical models of intrathecal delivery and the assessment of spinal pathologies arising from acute and chronic intrathecal drug delivery.   Chapters provide essential discussions of clinical aspects of patient care, including patient evaluation and screening, trialing and device management, troubleshooting problems and addressing complications, best practices, cost-effectiveness and future of the therapy. \u003c\/p\u003e\r\n\r\n\u003cp\u003eClinicians and researchers who practice intrathecal therapy and study neuraxial mechanisms will find \u003ci\u003eNeuraxial Therapeutics\u003c\/i\u003e,  to be an invaluable guide to this treatment modality.\u003c\/p\u003e\n\u003cp\u003e\u003c\/p\u003e\n\u003c\/div\u003e\u003cdiv\u003e\n\u003cp\u003eSalim M. Hayek, MD, PhD\u003c\/p\u003e\n\u003cp\u003eUniversity Hospitals of Cleveland\u003c\/p\u003e\n\u003cp\u003eDivision of Pain Medicine\u003c\/p\u003e\n\u003cp\u003eDepartment of Anesthesiology\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eCleveland, OH USA\u003c\/p\u003e\r\n\r\n\u003cp\u003e \u003c\/p\u003e\r\n\r\n\u003cp\u003eTony L. Yaksh, PhD\u003c\/p\u003e\r\n\r\n\u003cp\u003eUniversity of California, San Diego\u003c\/p\u003e\r\n\r\n\u003cp\u003eDepartment of Anesthesiology and Pharmacology\u003c\/p\u003e\r\n\r\n\u003cp\u003eLa Jolla, CA USA\u003c\/p\u003e\n\u003cbr\u003e\u003cp\u003e\u003c\/p\u003e\n\u003c\/div\u003e\u003cbr\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublication Date: \u003c\/td\u003e\n\u003ctd\u003e04 January 2025\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePublisher: \u003c\/td\u003e\n\u003ctd\u003eSpringer International Publishing\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eImprint: \u003c\/td\u003e\n\u003ctd\u003eSpringer\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eISBN-13: \u003c\/td\u003e\n\u003ctd\u003e9783031395604\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFormat: \u003c\/td\u003e\n\u003ctd\u003ePaperback \/ softback\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePage Count: \u003c\/td\u003e\n\u003ctd\u003e830\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e","brand":"Springer International Publishing","offers":[{"title":"Default Title","offer_id":49483872469132,"sku":"9783031395604","price":143.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9783031395604.jpg?v=1781086805","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9783031395604","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}