Subcellular Biochemistry: Functions and Mechanisms

Commisso, Cosimo

This book presents the functions and mechanisms of macropinocytosis, an actin-driven endocytic uptake process.

Key points, including the evolutionary origins of macropinocytosis and major signaling pathways that regulate this uptake mechanism, are highlighted. A wide-array of functions of macropinocytosis are described, including cellular metabolism, cell death, cell migration and antigen presentation. Macropinocytosis has recently been recognized as a critical pathway in disease pathology and treatment. Therefore, a broad overview of macropinocytosis will benefit clinicians, as well as translational and basic research scientists. Moreover, as one of the main clathrin-independent endocytic routes, compiling all the critical information about macropinocytosis in one collection, this book will also be helpful to educators and their students.

Details

Published by: Springer

Publication Date: 2022-04-06

Format: Hardcover

ISBN-13: 9783030940034

DOI: 10.1007/978-3-030-94004-1

Dimensions: 235cm x155cm

Pages: 224