{"product_id":"9783030456443","title":"Coenzyme Q in Aging","description":"\u003ch1\u003eCoenzyme Q in Aging\u003c\/h1\u003e \u003ch2\u003eLópez Lluch, Guillermo\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cdiv\u003e\u003cbr\u003e\u003c\/div\u003e\u003cdiv\u003e\n\u003cp\u003eThis book offers a comprehensive exploration of research on the essential relationship of the coenzyme Q\u003csub\u003e10\u003c\/sub\u003e and the process of aging in living organisms. CoQ\u003csub\u003e10\u003c\/sub\u003e is an important factor in two main aspects of cell physiology: bioenergetics and antioxidant protection. While primary deficiency of CoQ\u003csub\u003e10\u003c\/sub\u003e is associated with severe and lethal disease, secondary deficiency can be associated with the progression of mitochondrial dysfunction linked to the lessening of biological activities during aging.\u003cbr\u003e\u003c\/p\u003e\n\n\u003cp\u003eThe book is organized in four sections. The first offers an overview of the function of CoQ\u003csub\u003e10, \u003c\/sub\u003ehighlighting the two main functions of CoQ\u003csub\u003e10\u003c\/sub\u003e in cells: its essential role as electron transport chain member in mitochondria, and the protection of cell membranes against oxidation as one of the main endogenous-synthesized antioxidants. \u003c\/p\u003e\n\n\u003cp\u003eThe second section covers research on Coenzyme 10. Topics include studiesinvolving invertebrate models, mammal studies and the influence of CoQ\u003csub\u003e \u003c\/sub\u003eon\u003csub\u003e \u003c\/sub\u003elongevity. Also covered is research involving the role of CoQ in senescence-accelerated mice. \u003c\/p\u003e\n\nSection three examines the effects of reduced CoQ in human aging, as evident in mitochondrial dysfunction, metabolic syndrome, neurodegenerative disorders, immunosenescence and fertility and reproduction. \u003cp\u003e\u003c\/p\u003e\n\n\u003cp\u003eThe final section, Prolongevity effectors and Coenzyme Q, explores research into slowing or stopping the aging process. Coverage includes strategies including calorie restriction, and modulation of CoQ\u003csub\u003e10\u003c\/sub\u003e levels by induction of synthesis or by supplementation. \u003c\/p\u003e\n\n\u003cp\u003e\u003ci\u003eCoenzyme Q in Aging\u003c\/i\u003e benefits a broad readership of researchers, clinicians, educators and students interested in the biochemical and physiological effects of coenzyme Q and the importance of this molecule in aging process. \u003c\/p\u003e\n\u003c\/div\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 2021-08-08\u003c\/p\u003e \u003cp\u003eFormat: Paperback\u003c\/p\u003e \u003cp\u003eISBN-13: 9783030456443\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-3-030-45642-9\u003c\/p\u003e \u003cp\u003eDimensions: 235.0cm x155.0cm\u003c\/p\u003e \u003cp\u003ePages: 369.0\u003c\/p\u003e ","brand":"Springer International Publishing","offers":[{"title":"Default Title","offer_id":44809629859980,"sku":"9783030456443","price":152.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9783030456443.jpg?v=1763657097","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9783030456443","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}