{"product_id":"9783030430344","title":"Advances in Experimental Medicine and Biology: Clinical Perspectives: Past, Present and Future","description":"\u003ch1\u003eAdvances in Experimental Medicine and Biology: Clinical Perspectives: Past, Present and Future\u003c\/h1\u003e \u003ch2\u003eKleinerman, Eugenie S.; Gorlick, Richard\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eThis thoroughly revised second edition complied in 2 books is an up-to-date overview of the current clinical advances in sarcoma and osteosarcoma. The new edition features detailed, in-depth discussions of microRNAs in osteosarcoma, historical perspectives of chemotherapy in the treatment of the disease, tumor targeted IL12 therapy and HER2 targeted therapy, the role of enhancer elements in regulating the prometastatic transcriptional program and more. Further, these essential volumes also includes new insights on Wnt signaling in osteosarcoma, the role of genomics, genetically modified T-cell therapy, liquid biopsy, oncolytic viruses, immunophenotyping, receptor tyrosine kinases and epigenetic-focused approaches for treatment of osteosarcoma metastases, as well as thoughts on the current standard of treatment for patients suffering from these cancers. In the years since the previous edition, there have been numerous new developments in this rapidly changing field; this new edition is both timely and urgently needed. When taken together these companion volumes, \u003ci\u003eCurrent Clinical (Book 1) and Scientific (Book 2) Advances in Osteosarcoma,\u003c\/i\u003e are\u003ci\u003e \u003c\/i\u003ea timely and urgently needed guide for laboratory investigators and clinical oncologists focused in sarcoma.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 2021-06-02\u003c\/p\u003e \u003cp\u003eFormat: Paperback\u003c\/p\u003e \u003cp\u003eISBN-13: 9783030430344\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-3-030-43032-0\u003c\/p\u003e \u003cp\u003eDimensions: 254cm x178cm\u003c\/p\u003e \u003cp\u003ePages: 212\u003c\/p\u003e ","brand":"Springer International Publishing","offers":[{"title":"Default Title","offer_id":44398538031244,"sku":"9783030430344","price":161.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9783030430344_20bc28ae-7406-4470-911a-974a2be3adc7.jpg?v=1777376034","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9783030430344","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}