Advances in Experimental Medicine and Biology: From Basic Mechanisms to Clinics

Barrio, Rosa; Sutherland, James D.; Rodriguez, Manuel S.

This book, written by members of the European network PROTEOSTASIS, provides an up-to-date review of the research regarding protein homeostasis in health and disease. With new discoveries contributing to the increasing complexity of this topic, the book offers a detailed overview of the pathways regulating protein homeostasis, including autophagy and the ubiquitin protein family. Following a basic introduction, it explains how defects in protein homeostasis contribute to numerous pathologies, including cancer, neurodegeneration, inflammation and a number of rare diseases. In addition, it discusses, the role of protein homeostasis in cellular development and physiology. 

Highlighting the latest research in the field of protein homeostasis and its implications for various clinically relevant diseases, the book appeals to researchers and clinicians, while also offering a reference guide for scholars who are new to the field.

Details

Published by: Springer

Publication Date: 2020-04-10

Format: Hardcover

ISBN-13: 9783030382650

DOI: 10.1007/978-3-030-38266-7

Dimensions: 254cm x178cm

Pages: 348