This comprehensive reference explores the current and future state of biobehavioral markers in family resilience research, with special focus on linking biological and physiological measures to behavioral and health outcomes. It brings together the latest biobehavioral data on child-parent and couple relationships, adversity, and other key areas reflecting new technological advances in biobehavioral studies and translates these findings into implications for real-world practice and policy. The contributors’ insights on biomarkers apply to emerging topics of interest (e.g., molecular genetics) as well as familiar ones (e.g., stress). Their interdisciplinary perspective helps to elaborate on risk and resilience factors for those creating the next generation of evidence-based interventions.