{"product_id":"9783030042776","title":"Advances in Experimental Medicine and Biology: Sterol Specificity and Indirect Mechanisms","description":"\u003ch1\u003eAdvances in Experimental Medicine and Biology: Sterol Specificity and Indirect Mechanisms\u003c\/h1\u003e \u003ch2\u003eRosenhouse-Dantsker, Avia; Bukiya, Anna N.\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cp\u003eIn this book, renowned scientists describe the role of steroid chirality and modification of lipid membrane physical properties in the modulation of G protein-coupled receptors and ion channels. The application of commonly-used technical approaches such as mass spectrometry and nucleic magnetic resonance transfer spectroscopy for studies on cholesterol distribution and alteration of lipid bilayer characteristics is also discussed. \u003c\/p\u003eThis book offers comprehensive insights into the current understanding of cholesterol-driven modulation of protein function via mechanisms that extend beyond lipid-protein direct interactions.  In the first part, the chapters introduce the reader to the use of the chemical derivatives of cholesterol as a valuable laboratory tool in the studies of cholesterol-driven modulation of protein function. In the second part, examples of cholesterol-induced changes in membrane physical characteristics are presented and discussed in light of their multifaceted contribution to the effect of cholesterol on protein function. \u003cp\u003e\u003c\/p\u003e\u003cp\u003e The book will be of interest to undergraduate and graduate students as well as basic science and medical researchers with a keen interest in the biophysical properties of cholesterol and physiological consequences of cholesterol presence in biological systems.\u003cbr\u003e\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 2019-02-12\u003c\/p\u003e \u003cp\u003eFormat: Hardcover\u003c\/p\u003e \u003cp\u003eISBN-13: 9783030042776\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-3-030-04278-3\u003c\/p\u003e \u003cp\u003eDimensions: 235cm x155cm\u003c\/p\u003e \u003cp\u003ePages: 197\u003c\/p\u003e ","brand":"Springer International Publishing","offers":[{"title":"Default Title","offer_id":44398535049356,"sku":"9783030042776","price":161.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9783030042776.jpg?v=1777375658","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9783030042776","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}