{"product_id":"9783030007362","title":"Advances in Experimental Medicine and Biology","description":"\u003ch1\u003eAdvances in Experimental Medicine and Biology\u003c\/h1\u003e \u003ch2\u003eDjouder, Nabil\u003c\/h2\u003e \u003cp\u003eThis book reviews recent work on molecular chaperones of the prefoldin family from their discovery in Archaea to the basic clarification of their structure. Even though, there is still a lot to investigate in order to understand the roles and functions of prefoldins, some preliminary work suggests their contribution in assembly and activation of a variety of macromolecular complexes. Hence, the reader is introduced to recent structural findings via cryo-electron microscopy and to the importance of this particular group of proteins in health and disease.   This book also discusses the particular structure of the URI prefoldin-like complex. In addition, recent developments in the generation of URI mouse models speculate on the functions and emerging roles of the URI prefoldin-like complex in various cellular processes. This novel protein complex represents a unique cellular machinery, which molecular basis of its activity still remains to be determined.\u003c\/p\u003e\u003cp\u003eThis work is thus a guide to help researchers in the field to have a more comprehensive and critical view of the prefoldin world.\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer\u003c\/p\u003e \u003cp\u003ePublication Date: 2018-12-13\u003c\/p\u003e \u003cp\u003eFormat: Hardcover\u003c\/p\u003e \u003cp\u003eISBN-13: 9783030007362\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-3-030-00737-9\u003c\/p\u003e \u003cp\u003eDimensions: 254cm x178cm\u003c\/p\u003e \u003cp\u003ePages: 135\u003c\/p\u003e ","brand":"Springer International Publishing","offers":[{"title":"Default Title","offer_id":44541529849996,"sku":"9783030007362","price":98.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9783030007362.jpg?v=1776432484","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9783030007362","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}