{"product_id":"9781907673931","title":"Handbook of HER2-targeted agents in breast cancer","description":"\u003ch1\u003eHandbook of HER2-targeted agents in breast cancer\u003c\/h1\u003e \u003ch2\u003eAlvarez, Ricardo H; Cortés, Javier; Mattos-Arruda, Leticia; Falzon, Mary; Fasolo, Angelica; Gandy, Michael; Gianni, Luca; Harbeck, Nadia; Piccart, Martine; Zambelli, Stefania; Zardavas, Dimitrios\u003c\/h2\u003e \u003cp\u003e​Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death in women worldwide, accounting for nearly a quarter of the total new cancer cases each year.  Of these cases, approximately  15–25% overexpress HER2, a transmembrane RTK kinase that is associated with aggressive tumor growth and poor outcomes.  However, in the past decade, survival rates of patients with HER-positive breast cancer have significantly improved due to increased screening, HER2 testing, and breakthrough HER2-targeted drug therapies.\nHandbook of HER2-Targeted Agents in Breast Cancer  provides oncologists, primary care physicians, trainees and other healthcare providers with a concise, accessible, and up-to-date survey of the field, including a review of our current understanding of the biology of the HER2 pathway and the rationale for targeting it in early-stage and advanced breast cancer, an overview of HER2-testing, and evidence-based discussions of available HER2-targeted regimens in the adjuvant and metastatic settings.\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Springer Healthcare\u003c\/p\u003e \u003cp\u003ePublication Date: 2014-11-03\u003c\/p\u003e \u003cp\u003eFormat: Paperback\u003c\/p\u003e \u003cp\u003eISBN-13: 9781907673931\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-1-907673-94-8\u003c\/p\u003e \u003cp\u003eDimensions: 201cm x127cm\u003c\/p\u003e \u003cp\u003ePages: 96\u003c\/p\u003e ","brand":"Springer Healthcare Ltd.","offers":[{"title":"Default Title","offer_id":49940326711436,"sku":"9781907673931","price":44.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9781907673931.jpg?v=1779058065","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9781907673931","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}