{"product_id":"9781617379086","title":"Methods in Molecular Biology: From Bench to Bedside","description":"\u003ch1\u003eMethods in Molecular Biology: From Bench to Bedside\u003c\/h1\u003e \u003ch2\u003eSioud, Mouldy\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cp\u003eRNA interference has become a key method in the suppression of gene expression and the development of therapeutic agents, yet there is still the problem of delivery, stability, and the danger of off-target effects such as the silencing of unwanted genes and activation of innate immunity. In \u003cem\u003esiRNA and miRNA Gene Silencing: From Bench to Bedside\u003c\/em\u003e, expert researchers explore the most recent advances in siRNA design, expression, delivery, \u003cem\u003ein vivo\u003c\/em\u003e imaging, and methods to minimize siRNA’s unwanted effects and promote successful use in patients. As part of the highly successful \u003cem\u003eMethods in Molecular Biology™\u003c\/em\u003e series, the chapters focus on their respective subjects with easy-to-use, up-to-date information, including several step-by-step laboratory protocols on topics such as new delivery formulations and strategies with promising applications \u003cem\u003ein vitro \u003c\/em\u003eand \u003cem\u003ein vivo\u003c\/em\u003e, validated therapeutic target genes, and components of miRNA function, biogenesis, and interference with virus infection.\u003c\/p\u003e\n\u003cp\u003eComprehensive and cutting-edge, \u003cem\u003esiRNA and miRNA Gene Silencing: From Bench to Bedside\u003c\/em\u003e offers an excellent collection of chapters to aid all those with an interest in RNAi, gene regulation, and new therapies.\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Humana\u003c\/p\u003e \u003cp\u003ePublication Date: 2011-05-26\u003c\/p\u003e \u003cp\u003eFormat: Paperback\u003c\/p\u003e \u003cp\u003eISBN-13: 9781617379086\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-1-60327-547-7\u003c\/p\u003e \u003cp\u003eDimensions: cm xcm\u003c\/p\u003e \u003cp\u003ePages: 472\u003c\/p\u003e ","brand":"Humana Press","offers":[{"title":"Default Title","offer_id":46542707228812,"sku":"9781617379086","price":152.1,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9781617379086.jpg?v=1772842728","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9781617379086","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}