{"product_id":"9781607613398","title":"Methods in Molecular Biology: Methods and Protocols","description":"\u003ch1\u003eMethods in Molecular Biology: Methods and Protocols\u003c\/h1\u003e \u003ch2\u003eClarke, Duncan J.\u003c\/h2\u003e \u003cp\u003e\u003c\/p\u003e\u003cp\u003eDue to their importance to cell biology, DNA topology-altering enzymes, collectively DNA topoisomerases and gyrases, have been studied thoroughly from a biochemical perspective, yet the expansion of research at the molecular and cellular levels continues to show a great deal of promise. In \u003cem\u003eDNA Topoisomerases: Methods and Protocols\u003c\/em\u003e, experts in the field present a compendium of protocols that extends into the new areas of research that have been recently uncovered in order to elucidate the methodology needed to study topoisomerases in the molecular and cellular context. The volume examines subjects such as the analysis of DNA topologies and the interaction of topoisomerases with DNA as tools to measure topoisomerase functions, the binding of topoisomerases to specific sites in the genomes of eukaryotes, including origins of DNA replication, as well as exploration of perturbed topoisomerase function. As a volume in the highly successful \u003cem\u003eMethods in Molecular Biology™\u003c\/em\u003e series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, laboratory protocols, and notes on trouble-shooting and avoiding known pitfalls.\u003c\/p\u003e\n\u003cp\u003eCutting-edge and easy-to-use, \u003cem\u003eDNA Topoisomerases: Methods and Protocols\u003c\/em\u003e provides key content which reflects an expanded understanding of the functions of these essential enzymes in the hope of inspiring researchers to further important discoveries in this dynamic field.\u003c\/p\u003e \u003ch3\u003eDetails\u003c\/h3\u003e \u003cp\u003ePublished by: Humana\u003c\/p\u003e \u003cp\u003ePublication Date: 2009-09-25\u003c\/p\u003e \u003cp\u003eFormat: Hardcover\u003c\/p\u003e \u003cp\u003eISBN-13: 9781607613398\u003c\/p\u003e \u003cp\u003eDOI: 10.1007\/978-1-60761-340-4\u003c\/p\u003e \u003cp\u003eDimensions: 260cm x193cm\u003c\/p\u003e \u003cp\u003ePages: 268\u003c\/p\u003e ","brand":"Humana Press","offers":[{"title":"Default Title","offer_id":46542431191180,"sku":"9781607613398","price":98.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0710\/9545\/1788\/files\/9781607613398.jpg?v=1772841462","url":"https:\/\/fh90cf-fv.myshopify.com\/products\/9781607613398","provider":"Late Knight Books and Services, LLC","version":"1.0","type":"link"}